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首页> 外文期刊>Revista Cubana de Hematología, Inmunología y Hemoterapia >Mastocytosis
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Mastocytosis

机译：肥大细胞增多症

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Mastocytoses are included among the group of "rare diseases" due to their low frequency. They are characterized by the growth and accumulation of mastocytes on the skin and other organs for no known reason. Clinical manifestations are due to infiltration by mastocytes and the release of chemical mediators. The diagnosis is clinical and based on histopathological findings from biopsies of the skin and other organs affected, such as the bone marrow. On the skin, the illness is manifested as urticaria pigmentosa. Several classifications have been made, but none has been universally accepted. Treatment is symptomatic and does not change the course of the illness. Most patients present symptoms related to mastocyte mediator release, and prevention of its effects on tissues is crucial to the treatment.
机译：肥大细胞酶由于其频率低而被包括在“罕见疾病”组中。它们的特征是不明原因的皮肤和其他器官中肥大细胞的生长和积累。临床表现是由于肥大细胞浸润和化学介质的释放。该诊断是临床的，并且基于皮肤和其他受影响器官（如骨髓）的活检组织病理学发现。在皮肤上，疾病表现为色素性荨麻疹。已经进行了几种分类，但是没有一个被普遍接受。治疗是对症治疗，不会改变病程。大多数患者表现出与肥大细胞介质释放有关的症状，而预防其对组织的影响对治疗至关重要。

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