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首页> 外文期刊>Romanian Journal of Biophysics >THE INFLUENCE OF 50 Hz MAGNETIC FIELD ON LIVER FUNCTION
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THE INFLUENCE OF 50 Hz MAGNETIC FIELD ON LIVER FUNCTION

机译：50 Hz磁场对肝脏功能的影响

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The present study has been conducted to evaluate the influence different intensities of 50 Hz magnetic field on some liver function tests such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), bilirubin, albumin and protein. The study also involved the effect of magnetic field on the oxidative state of the liver tissue. The study was conducted on about 80 Sparague-Dawely male rats of an average weight of 140–160 g. The exposure period was 2 hours/day for two weeks. The sera taken from control and exposed rats were also examined spectroscopically. The results showed an increase (p 90%), while albumin and alanine aminotransferase changed with about 11% and 22% respectively. The applied field also caused an increase in the liver lipid peroxidation and a decrease (p < 0.05) in glutathione concentration. Results consequently, suggest that the redox potential of both glutathione (GSH/GSSG) and nicotinamide dinucleotide (NADH/NAD) are disturbed as a result of exposure. Precursors of NADH, as a result of its exhaustion, such as kynurenine, tyrosine and tryptophan, might be also affected.
机译：本研究旨在评估不同强度的50 Hz磁场对某些肝功能测试的影响，例如丙氨酸氨基转移酶（ALT），天冬氨酸氨基转移酶（AST），碱性磷酸酶（ALP），胆红素，白蛋白和蛋白质。该研究还涉及磁场对肝组织氧化状态的影响。该研究是在约80只Sparague-Dawely雄性大鼠上进行的，平均体重为140-160 g。暴露期为每天2小时/两周。取自对照和暴露的大鼠的血清也进行了光谱检查。结果显示增加（p 90％），而白蛋白和丙氨酸转氨酶分别变化约11％和22％。该应用领域还引起肝脏脂质过氧化作用的增加和谷胱甘肽浓度的降低（p <0.05）。结果表明，由于暴露，谷胱甘肽（GSH / GSSG）和烟酰胺二核苷酸（NADH / NAD）的氧化还原电位均受到干扰。由于其耗尽，NADH的前体如犬尿氨酸，酪氨酸和色氨酸也可能受到影响。

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