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首页> 外文期刊>Open Journal of Obstetrics and Gynecology >Tubal Infertility and Chlamydia Trachomatis in a Congolese Infertile Population
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Tubal Infertility and Chlamydia Trachomatis in a Congolese Infertile Population

机译:刚果不育人群中的输卵管不育和沙眼衣原体

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Infertility of tubal origin is the most frequent in sub-Saharan area. It is due to tuboperitoneal lesions mainly because of infection; especially sexually transmitted infection. Worldwide, Chlamydia trachomatis is the main pathogen. In our setting, some studies failed to establish the link between tubal infertility and chlamydia trachomatis. The current study aimed to determine the local data related to chlamydia trachomatis role in tubal infertility and the usefulness of Chlamydia trachomatis antibody titer test (CAT) in discrimination of the patients with and without tuboperitoneal lesions. Patients’ average age was 33.9 ± 4.8 years, average coitarche 19.4 ± 4.4 years and average number of partners: 3.1 ± 1.6. The level of CAT is correlated to the tuboperitoneal severity. CAT was more specific (93.3%; CI 95%: 81.7 - 98.6) than sensitive (72.7% CI 95%: 49.8 - 89.3) and discriminated correctly 89% (AUC = 0.89) of the patients with or without tuboperitoneal lesions. In conclusion, as it is stated worldwide, Chlamydia trachomatis is the most frequent sexually transmitted pathogen associated with tubal infertility. CAT has to be used as a tool to select patients to be submitted to invasive investigation, like laparoscopy.
机译:输卵管起源的不孕症在撒哈拉以南地区最常见。主要由于感染引起的肾小管腹膜病变;特别是性传播感染。在全球范围内,沙眼衣原体是主要病原体。在我们的研究中,一些研究未能建立输卵管性不育与沙眼衣原体之间的联系。当前的研究旨在确定与沙眼衣原体在输卵管不育中的作用有关的本地数据,以及沙眼衣原体抗体滴度测试(CAT)在区分有无肾小管腹膜病变患者中的有用性。患者的平均年龄为33.9±4.8岁,平均耳鼻喉科的平均年龄为19.4±4.4岁,伴生的平均人数为3.1±1.6。 CAT的水平与肾小管腹膜的严重程度相关。 CAT比敏感的(72.7%CI 95%:49.8-89.3)更具有特异性(93.3%; CI 95%:81.7-98.6),并且可以正确区分89%(AUC = 0.89)有或没有肾小管腹膜病变的患者。综上所述,沙眼衣原体是全世界最常见的与输卵管性不育有关的性传播病原体。 CAT必须用作选择要进行侵入性检查(例如腹腔镜检查)的患者的工具。

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