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Periacetabular Brucella Osteomyelitis

机译:髋臼周围布鲁氏菌性骨髓炎

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Introduction: Although Brucellosis has a limited geographic distribution; it remains a challenge in certain parts of the world such as in Mediterranean, western Asian, Latin American and African regions. We present a unique case of periacetabular Brucella osteomyelitis and increase awareness of possible widespread distrubition of Brucella osteomyelitis and its ability to affect any region of the musculoskeletal system. Case Presentation: A 44-year-old male farmer presented with symptoms of pain radiating from his left hip to his thigh of five years duration. There was a history of night sweats and fever for the past two months. A lytic area with smooth borders in left periacetabular region was detected on pelvic roentgenography of the patient. Magnetic resonance imaging revealed a cavitatory lesion in relation to hip joint. Open biopsy was undertaken with the differential diagnosis of an infectious (Brucella or Tuberculous) or tumoral lesion. Intraoperative frozen sections showed granulomatous inflammatory tissue. Post debridement, the cavity was filled with autograft taken from the patient’s right iliac wing. Postoperative immunohistochemistry confirmed diagnosis of Brucella osteomyelitis. Oral Doxycyline, Rifampicine and Ciprofloxacin were administered for 3 months. At one-year postoperatively, the patient had a painless, unrestricted range of motion and function in relation to the affected hip. Conclusion: In endemic regions, Brucella osteomyelitis should be considered in differential diagnosis in patients with arthralgia and/or spondylodiscitis in the presence of radiologically suspected osseous lesions.
机译:简介:尽管布鲁氏菌病的地理分布有限;在世界某些地区,例如地中海,西亚,拉丁美洲和非洲地区,这仍然是一个挑战。我们提出了髋臼周围布鲁氏菌骨髓炎的独特案例,并提高了布鲁氏菌骨髓炎可能广泛分布的认识,以及其影响肌肉骨骼系统任何区域的能力。病例介绍:一名44岁的男性农民出现了从左髋到大腿持续5年的疼痛症状。过去两个月有盗汗和发烧的历史。在患者的骨盆X光检查中发现左髋臼周围区域边界光滑的溶胞区域。磁共振成像显示与髋关节有关的空化病变。进行开放活检,以鉴别诊断感染性(布鲁氏菌或结核性)或肿瘤性病变。术中冰冻切片显示肉芽肿性炎症组织。清创后,腔内充满了从患者右翼取来的自体移植物。术后免疫组织化学证实布鲁氏菌骨髓炎的诊断。口服强力霉素,利福平和环丙沙星治疗3个月。术后一年,患者相对于患髋具有无痛,无限制的运动和功能范围。结论:在地方性地区,如果存在放射性疑似骨性病变,则在关节痛和/或脊椎盘炎患者中应考虑布鲁氏菌性骨髓炎进行鉴别诊断。

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