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Contraception and endometriosis: challenges, efficacy, and therapeutic importance

机译:避孕和子宫内膜异位:挑战,疗效和治疗重要性

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Abstract: Endometriosis is a benign gynecological condition that is estimated to affect 10% of women in the general population and appears to be increasing in incidence. It is an estrogen-dependent inflammatory disease, and is primarily characterized by dysmenorrhea, deep dyspareunia, chronic pelvic pain, and variable effects on fertility. The symptoms may greatly affect quality of life, and symptom control may be the primary aim of initial management, while contraceptive effect is often secondary. It is estimated that 30%–50% of women with endometriosis have an infertility problem, so a considerable number of endometriosis sufferers will require effective, planned contraception to maximize “protection of fertility” and prevent progression of the endometriotic condition. Ideally, this contraception should also provide symptom relief and improvement of physical, mental, and social well-being. At the present time, long-term progestogens appear to be the most effective choice for meeting all of these requirements, but other options need to be considered. It is becoming increasingly recognized that hormonal contraceptive systems are necessary for prevention of disease recurrence following surgical treatment of endometriosis. The personal preferences of the woman are an integral part of the final contraceptive choice. This article discusses the advantages and disadvantages of the contraceptive options available to women with endometriosis.
机译:摘要:子宫内膜异位症是一种良性妇科疾病,估计会影响普通人群中10%的女性,而且发病率似乎正在增加。它是一种依赖雌激素的炎症性疾病,主要特征是痛经,深度性痛经,慢性盆腔痛以及对生育的影响不一。这些症状可能会极大地影响生活质量,而症状控制可能是最初治疗的主要目的,而避孕作用往往是次要的。据估计,有30%–50%的子宫内膜异位症妇女有不孕问题,因此,相当多的子宫内膜异位症患者将需要有效的计划生育,以最大程度地“保护生育力”并防止子宫内膜异位症的进展。理想情况下,这种避孕方法还可以缓解症状,并改善身体,心理和社会福祉。目前,长期孕激素似乎是满足所有这些要求的最有效选择,但还需要考虑其他选择。人们越来越认识到,激素避孕系统对于预防子宫内膜异位症的手术治疗后疾病的复发是必要的。女人的个人喜好是最终避孕选择的组成部分。本文讨论了子宫内膜异位症妇女可以使用的避孕方法的优缺点。

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