...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Sao Paulo Medical Journal >HTLV-I infection and adult T-cell leukemia in Brazil: an overview
【24h】

HTLV-I infection and adult T-cell leukemia in Brazil: an overview

机译：巴西HTLV-I感染和成人T细胞白血病：概述

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Human T-cell lymphotropic Virus Type I (HTLV-I) is the etiologic factor for adult T-cell leukemia/lymphoma (ATL). HTLV-I infection can also lead to other diseases, such as HTLV -I-associated myelopathy/tropical spastic paraparesis (HAM/TSP), uveitis, arthropathy and infectious dermatitis. Studies of the infectious mode of transmission of HTLV-I and risk factors for HTLV-I-related diseases have been conducted in several countries, and differences in the prevalence, age patterns, ethnic groups and clinical presentation of the related diseases have been described worldwide. Based on the geographical characteristics of Brazil and data from the literature, we have summarized the distribution of seroprevalence in blood donors in different states around the country, as well as the incidence of ATL in regards to the endemic foci. ATL in Brazil has the same characteristics as those described elsewhere, but is reported more frequently at a younger age. In order to better evaluate ATL in Brazil, a registry has been established at the several hematologic centers under the sponsorship of the Instituto Nacional de Cancer and the Brazilian Society of Hematology and Hemotherapy, for the purpose of recording all cases originally diagnosed in Brazil.
机译：I型人T细胞淋巴病毒（HTLV-1）是成人T细胞白血病/淋巴瘤（ATL）的病因。 HTLV-I感染还可能导致其他疾病，例如与HTLV-I相关的脊髓病/热带痉挛性轻瘫（HAM / TSP），葡萄膜炎，关节病和感染性皮炎。几个国家已经对HTLV-I的传染性传播方式和与HTLV-I相关的疾病的危险因素进行了研究，并且全球范围内已经描述了相关疾病的流行，年龄模式，种族和临床表现的差异。根据巴西的地理特征和文献数据，我们总结了全国不同州的献血者血清阳性率的分布以及地方病灶的ATL发生率。巴西的ATL具有与其他地方所描述的相同的特征，但是在年轻时据报道更为频繁。为了更好地评估巴西的ATL，在国家癌症研究所和巴西血液与血液疗法学会的赞助下，在几个血液学中心建立了一个注册表，目的是记录最初在巴西诊断出的所有病例。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号