...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Sao Paulo Medical Journal >Insulin autoimmune syndrome: case report
【24h】

Insulin autoimmune syndrome: case report

机译：胰岛素自身免疫综合征：病例报告

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

CONTEXT: Insulin autoimmune syndrome (IAS, Hirata disease) is a rare cause of hypoglycemia in Western countries. It is characterized by hypoglycemic episodes, elevated insulin levels, and positive insulin antibodies. Our objective is to report a case of IAS identified in South America. CASE REPORT: A 56-year-old Caucasian male patient started presenting neuroglycopenic symptoms during hospitalization due to severe trauma. Biochemical evaluation confirmed hypoglycemia and abnormally high levels of insulin. Conventional imaging examinations were negative for pancreatic tumor. Insulin antibodies were above the normal range. Clinical remission of the episodes was not achieved with verapamil and steroids. Thus, a subtotal pancreatectomy was performed due to the lack of response to conservative treatment and because immunosuppressants were contraindicated due to bacteremia. Histopathological examination revealed diffuse hypertrophy of beta cells. The patient continues to have high insulin levels but is almost free of hypoglycemic episodes.
机译：背景：胰岛素自身免疫综合征（IAS，平田病）是西方国家低血糖的罕见原因。它的特点是降血糖发作，胰岛素水平升高和胰岛素抗体阳性。我们的目标是报告在南美发现的一例IAS。病例报告：一名56岁的白人男性患者由于严重的创伤在住院期间开始表现出神经糖尿症状。生化评估证实低血糖和异常高水平的胰岛素。常规影像学检查胰腺癌阴性。胰岛素抗体高于正常范围。维拉帕米和类固醇未能达到发作的临床缓解。因此，由于缺乏对保守治疗的反应，并且由于菌血症而禁忌了免疫抑制剂，因此进行了胰腺全切除术。组织病理学检查显示β细胞弥漫性肥大。该患者继续具有高胰岛素水平，但几乎没有降血糖发作。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号