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Alginate dressings for treating pressure ulcers

机译：海藻酸盐敷料治疗压疮

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ABSTRACT BACKGROUND: Pressure ulcers, also known as bedsores, decubitus ulcers and pressure injuries, are localised areas of injury to the skin or the underlying tissue, or both. Dressings are widely used to treat pressure ulcers and there are many options to choose from including alginate dressings. A clear and current overview of current evidence is required to facilitate decision-making regarding dressing use for the treatment of pressure ulcers. This review is part of a suite of Cochrane reviews investigating the use of dressings in the treatment of pressure ulcers. Each review will focus on a particular dressing type. OBJECTIVES: To assess the effects of alginate dressings for treating pressure ulcers in any care setting. METHODS: Search methods: For this review, in April 2015 we searched the following databases the Cochrane Wounds Group Specialised Register; The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library); Ovid MEDLINE; Ovid MEDLINE (In-Process & Other Non-Indexed Citations); Ovid EMBASE; and EBSCO CINAHL. There were no restrictions based on language or date of publication. Selection criteria: Published or unpublished randomised controlled trials (RCTs) comparing the effects of alginate with alternative wound dressings or no dressing in the treatment of pressure ulcers (stage II or above). Data collection and analysis: Two review authors independently performed study selection, risk of bias assessment and data extraction. MAIN RESULTS: We included six studies (336 participants) in this review; all studies had two arms. The included studies compared alginate dressings with six other interventions that included: hydrocolloid dressings, silver containing alginate dressings, and radiant heat therapy. Each of the six comparisons included just one study and these had limited participant numbers and short follow-up times. All the evidence was of low or very low quality. Where data were available there was no evidence of a difference between alginate dressings and alternative treatments in terms of complete wound healing or adverse events. AUTHORS' CONCLUSIONS: The relative effects of alginate dressings compared with alternative treatments are unclear. The existing trials are small, of short duration and at risk of bias. Decision makers may wish to consider aspects such as cost of dressings and the wound management properties offered by each dressing type, for example, exudate management.
机译：背景技术压疮，也称为褥疮，褥疮性溃疡和压伤，是皮肤或下面的组织或两者的局部损伤区域。敷料被广泛用于治疗压疮，包括藻酸盐敷料在内有很多选择。需要对当前证据进行清晰，最新的概述，以促进有关敷料用于治疗压疮的决策。该评价是一组Cochrane评价的一部分，该评价研究了在压力性溃疡的治疗中使用敷料的情况。每个评论都将针对特定的敷料类型。目的：评估藻酸盐敷料在任何护理环境中治疗压疮的效果。方法：搜索方法：在本次审查中，我们于2015年4月搜索了以下数据库，即Cochrane伤口小组专业注册簿;科克伦对照试验中央注册簿（中央）（科克伦图书馆）; Ovid MEDLINE; Ovid MEDLINE（进行中的和其他非索引引文）; Ovid EMBASE;和EBSCO CINAHL。没有基于语言或发布日期的限制。选择标准：已发表或未发表的随机对照试验（RCT），比较了藻酸盐与替代伤口敷料或无敷料治疗压疮的效果（II期以上）。数据收集和分析：两位评价作者独立进行研究选择，偏倚评估风险和数据提取。主要结果：我们纳入了六项研究（336名参与者）。所有研究都有两条手臂。纳入的研究将藻酸盐敷料与其他六种干预措施进行了比较，其中包括：水胶体敷料，含银藻酸盐敷料和辐射热疗。六项比较中的每项仅包括一项研究，参与者人数有限且随访时间短。所有证据均为低质量或非常低质量。在可获得数据的地方，没有证据表明藻酸盐敷料和替代疗法在伤口完全愈合或不良事件方面有差异。作者的结论：与替代疗法相比，藻酸盐敷料的相对作用尚不清楚。现有的试验规模小，持续时间短并且有偏见的风险。决策者可能希望考虑诸如敷料成本和每种敷料类型所提供的伤口管理特性（例如渗出物管理）等方面。

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