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首页> 外文期刊>Sao Paulo Medical Journal >Prevalence of allergen sensitization, most important allergens and factors associated with atopy in children
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Prevalence of allergen sensitization, most important allergens and factors associated with atopy in children

机译:儿童过敏原致敏率,最重要的过敏原和与特应性相关的因素

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CONTEXT AND OBJECTIVE: Knowledge of the profile of allergen sensitization among children is important for planning preventive measures. The objective of this study was to assess the prevalence and profile of sensitization to inhaled allergens and food among children and adolescents in an outpatient population in the city of Palmas. DESIGN AND SETTING: Cross-sectional study at outpatient clinics in Palmas, Tocantins, Brazil. METHODS: Ninety-four patients aged 1-15 years who were attending two pediatric outpatient clinics were selected between September and November 2008. All of the subjects underwent clinical interviews and skin prick tests. RESULTS: A positive skin prick test was observed in 76.6% of the participants (72.3% for inhalants and 28.9% for food allergens). The most frequent allergens were Dermatophagoides pteronyssinus (34%), cat epithelium (28.7%), dog epithelium (21.3%), Dermatophagoides farinae (19.1%), Blomia tropicalis (18.1%), cow's milk (9.6%) and grasses (9.6%). A positive skin prick test correlated with a history of atopic disease (odds ratio, OR = 5.833; P = 0.002), a family history of atopic disease (OR = 8.400; P 0.001), maternal asthma (OR = 8.077; P = 0.048), pet exposure (OR = 3.600; P = 0.012) and cesarean delivery (OR = 3.367; P = 0.019). CONCLUSION: Dermatophagoides pteronyssinus was the most frequent aeroallergen and cow’s milk was the most prevalent food allergen. There was a positive correlation between a positive skin prick test and several factors, such as a family history of atopic disease, maternal asthma, pet exposure and cesarean delivery.
机译:内容与目的:了解儿童过敏原的概况对于计划预防措施很重要。这项研究的目的是评估帕尔马斯市门诊人口中儿童和青少年对吸入性过敏原和食物致敏的发生率和概况。设计与环境:在巴西托坎丁斯帕尔马斯的门诊进行横断面研究。方法:选择2008年9月至2008年11月间在两家儿科门诊就诊的1-15岁的94例患者。所有受试者均接受了临床访谈和皮肤点刺测试。结果:76.6%的参与者皮肤刺痛试验呈阳性(吸入剂为72.3%,食物过敏原为28.9%)。最常见的变应原是鹿角皮癣(34%),猫上皮(28.7%),狗上皮(21.3%),粉状皮肤癣菌(19.1%),热带大麦(18.1%),牛奶(9.6%)和草(9.6) %)。皮肤点刺试验阳性与特应性病史相关(比值比,OR = 5.833; P = 0.002),特应性疾病家族史(OR = 8.400; P <0.001),孕产妇哮喘(OR = 8.077; P = 0.048),宠物暴露(OR = 3.600; P = 0.012)和剖宫产(OR = 3.367; P = 0.019)。结论:鹿角皮癣是最常见的空气过敏原,牛奶是最普遍的食物过敏原。皮肤点刺试验阳性与多种因素之间存在正相关,例如特应性疾病的家族病史,母体哮喘,宠物接触和剖宫产。

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