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首页> 外文期刊>Saudi journal of kidney diseases and transplantation : >Pregnancy-related acute kidney injury: Etiologies and short-term outcomes in a tertiary hospital in Southwest Nigeria
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Pregnancy-related acute kidney injury: Etiologies and short-term outcomes in a tertiary hospital in Southwest Nigeria

机译：妊娠相关的急性肾损伤：尼日利亚西南部一家三级医院的病因和近期预后

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Although the incidence of pregnancy-related acute kidney injury (PRAKI) is declining in developing countries, it still remains a major cause of maternal and fetal morbidity and mortality. The aim of this study was to determine the etiologies, short-term outcomes, and their predictors in patients with PRAKI managed in a tertiary health facility in Southwest Nigeria over a four-year period. This was a four-year retrospective review of clinical records of patients managed for PRAKI in University of Medical Sciences Teaching Hospital, Ondo State, Nigeria. Thirty-two women with a mean age of 31.09 ± 7.50 years had PRAKI during the period reviewed. Twenty-four (75%) patients were multiparous and PRAKI was most common in the postpartum period (56.3%). Twenty-three patients (71.9%) were in RIFLE Stage 3, 24 (75%) received blood transfusion, 5 (15.6%) required intensive care unit (ICU) care, 24 (75%) needed dialysis while 19 (59.4%) had hemodialysis. The common causes of PRAKI were obstetric hemorrhage in 16 (50%), sepsis in seven (21.9%), and eclampsia in six (18.8%). Maternal and fetal mortality were 34.4% and 50% respectively. Seventeen (53.1%) had full renal recovery and only one (3.1%) became dialysis dependent. Significant factors that were associated with maternal mortality were admission to ICU (P = 0.01), hypotension (P = 0.02), and impaired consciousness (P 0.001) PRAKI is still relatively common and significantly contributes to maternal and perinatal mortality in Nigeria. Obstetric hemorrhage which is the most common cause of PRAKI is preventable and treatable. There is a need for physicians to effectively prevent and manage obstetric hemorrhage.
机译：尽管在发展中国家，与妊娠相关的急性肾损伤（PRAKI）的发病率正在下降，但它仍然是孕产妇和胎儿发病率和死亡率的主要原因。这项研究的目的是确定尼日利亚西南部三级卫生机构管理的PRAKI患者的病因，短期结局及其预测因素，为期四年。这是对尼日利亚Ondo State的医学大学教学医院的PRAKI治疗患者的临床记录的四年回顾性回顾。在本报告所述期间，三十二名平均年龄为31.09±7.50岁的妇女患有PRAKI。二十四（75％）位患者是多胎的，PRAKI最常见于产后（56.3％）。处于RIFLE第三阶段的23例患者（71.9％），24例（75％）接受了输血，5例（15.6％）需要重症监护病房（ICU）护理，24例（75％）需要透析，19例（59.4％）进行过血液透析。 PRAKI的常见原因是产科出血16例（50％），败血症7例（21.9％）和子痫6例（18.8％）。孕产妇和胎儿死亡率分别为34.4％和50％。十七名（53.1％）的肾功能完全恢复，只有一名（3.1％）依赖透析。与孕产妇死亡率相关的重要因素是入住ICU（P = 0.01），低血压（P = 0.02）和意识障碍（P <0.001）PRAKI仍然相对普遍，并且在尼日利亚造成孕产妇和围产期死亡率的显着原因。产科出血是PRAKI最常见的原因，是可以预防和治疗的。需要医生有效地预防和管理产科出血。

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