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首页> 外文期刊>Signal transduction and targeted therapy. >Controlled drug delivery vehicles for cancer treatment and their performance
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Controlled drug delivery vehicles for cancer treatment and their performance

机译：用于癌症治疗的受控药物输送工具及其性能

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Although conventional chemotherapy has been successful to some extent, the main drawbacks of chemotherapy are its poor bioavailability, high-dose requirements, adverse side effects, low therapeutic indices, development of multiple drug resistance, and non-specific targeting. The main aim in the development of drug delivery vehicles is to successfully address these delivery-related problems and carry drugs to the desired sites of therapeutic action while reducing adverse side effects. In this review, we will discuss the different types of materials used as delivery vehicles for chemotherapeutic agents and their structural characteristics that improve the therapeutic efficacy of their drugs and will describe recent scientific advances in the area of chemotherapy, emphasizing challenges in cancer treatments.
机译：尽管常规化学疗法在某种程度上已经成功，但是化学疗法的主要缺点是其生物利用度差，高剂量需求，不良副作用，低治疗指数，多种耐药性的产生以及非特异性靶向。开发药物输送工具的主要目的是成功解决这些与输送有关的问题，并将药物运送到所需的治疗作用部位，同时减少不良副作用。在这篇综述中，我们将讨论用作化学治疗剂递送工具的不同类型的材料及其结构特征，这些材料可改善其药物的治疗功效，并描述化学疗法领域的最新科学进展，强调癌症治疗中的挑战。

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