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首页> 外文期刊>Southern African Journal of Infectious Diseases >Multidrug-resistant nosocomial infections among private hospital patients in the North West province
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Multidrug-resistant nosocomial infections among private hospital patients in the North West province

机译：西北省私立医院患者的耐多药医院感染

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This article reports on severe clinical cases of nosocomial infections that were caused by multidrug-resistant (MDR) isolates of Acinetobacter baumannii and Pseudomonas aeruginosa in an intensive care unit (ICU). Globally, patients in ICUs have encountered an increasing emergence and spread of MDR pathogens. A retrospective case study was conducted to investigate the possible causes and occurrence of nosocomial infections linked to reported cases thereof in a private hospital in the North West province between December 2009 and August 2010. This followed an enquiry from a concerned community member about two patient deaths and a patient who was in the hospital's ICU between July and August 2010 with an infection by an unknown “superbug” Of the 24 adult patients who were admitted to the ICU in the study period, 22 presented with isolates of A. baumannii , one with P. aeruginosa , and one with presumed A. baumannii for which there was no laboratory test confrmation. Of those who were infected with A. baumannii , nine of the 22 died (a case fatality rate of 41%). The patient with no laboratory test confrmation also died within seven days, while the patient who was infected with P. aeruginosa was still in hospital at the end of the study period (August 2010). The average length of stay in the hospital was 21.3 days. Six of the 24 patients (25%) stayed longer than 30 days. A patient who was infected with P. aeruginosa stayed even longer. The most common cause of death among the ICU patients, notwithstanding other underlying conditions, was A. baumannii strain, which may have directly or indirectly contributed to the prolonged length of stay in hospital. It is possible that P. aeruginosa is a recent introduction to this ICU.
机译：本文报道了重症监护病房（ICU）中鲍曼不动杆菌和铜绿假单胞菌的多药耐药性（MDR）分离株引起的严重医院感染临床病例。在全球范围内，ICU患者的MDR病原体出现和扩散不断增加。在2009年12月至2010年8月之间，在西北省的一家私立医院中进行了一项回顾性病例研究，以调查与报告的病例相关的医院感染的可能原因和发生情况。此前，有关社区成员询问了两名患者死亡的情况。在研究期间入院ICU的24名成年患者中，有22名患者出现了 A分离株，其中一名患者在2010年7月至8月之间在医院的ICU中感染了未知的“超级病菌”。鲍曼尼氏菌，具有 P。铜绿假单胞菌和一个带有 A的假单胞菌。鲍曼氏菌没有实验室检验确认。在那些感染了 A的人群中。鲍曼尼22例中有9例死亡（病死率为41％）。没有实验室检查证实的患者在7天之内也死亡，而感染了iP的患者。在研究期末（2010年8月），铜绿假单胞菌仍在医院中。在医院的平均住院时间为21.3天。 24名患者中有6名（25％）的住院时间超过30天。感染了 P的患者。铜绿花呆了更长的时间。尽管有其他潜在疾病，ICU患者中最常见的死亡原因是 A。鲍曼氏菌株，可能直接或间接导致住院时间延长。 P。铜绿是该ICU的最新介绍。

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