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首页> 外文期刊>Sri Lanka Journal of Psychiatry >Psychopathology in patients with schizophrenia attending a psychiatry outpatient clinic at a tertiary care hospital
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Psychopathology in patients with schizophrenia attending a psychiatry outpatient clinic at a tertiary care hospital

机译：三级医院精神科门诊就诊的精神分裂症患者的精神病理学

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NOTE: the name of the third author was changed from Anuradha TO Arjuna on 30/06/2011.Background Patients with schizophrenia who are not acutely ill continue to experience different levels of psychopathology, despite a relatively stable lifestyle. Aims To describe the pattern of symptoms in patients with schizophrenia attending an outpatient clinic using the Brief Psychiatric Rating Scale Expanded version (BPRS-E). Methods Consecutive patients in an outpatient clinic, with a diagnosis of schizophrenia were assessed. Analysis was based on the four-factor cluster of symptoms: thought disturbance, animation, mood disturbance and apathy identified using the BPRS-E. Results Sample size was 178 (males 54.5 %, mean age = 39.29 years, mean illness duration = 13.29 years, mean total BPRS score = 32.11). Apathy had the highest mean score among the symptom clusters (6.54, SD 3.56), while blunted affect (1.87, SD 1.23) and emotional withdrawal (1.85, SD 1.26) had highest individual item mean scores. Patients on clozapine had significantly more symptoms of thought disturbance and animation compared to others, (P 400mg) had significantly higher scores in thought disturbance and apathy. Higher scores on total BPRS, negative symptoms and thought disturbance were associated with lower levels of functioning. Conclusions Patients with schizophrenia on treatment continue to have symptoms. Negative symptoms are the most predominant. Patients on clozapine have a higher level of psychopathology. The degree of negative symptoms and thought disturbance had a significant association with the level of functioning. DOI: http://dx.doi.org/10.4038/sljpsyc.v2i1.3162 SL J Psychiatry 2011; 2 (1): 23-27
机译：注意：第三作者的名字在2011年6月30日从Anuradha更改为Arjuna。背景尽管生活相对稳定，但并非急性病的精神分裂症患者仍会经历不同程度的心理病理学。目的使用简明精神病评定量表扩展版（BPRS-E）来描述在门诊就诊的精神分裂症患者的症状模式。方法对连续门诊诊断为精神分裂症的患者进行评估。分析基于症状的四因素组：思维障碍，动画，情绪障碍和使用BPRS-E识别出的冷漠。结果样本量为178（男性为54.5％，平均年龄= 39.29岁，平均病程= 13.29岁，平均BPRS总得分= 32.11）。在症状群中，冷漠的平均得分最高（6.54，SD 3.56），而钝痛（1.87，SD 1.23）和情绪退缩（1.85，SD 1.26）的单项平均得分最高。氯氮平患者的思维障碍和动静症状明显多于其他人（P 400mg），其思想障碍和冷漠得分更高。总BPRS得分较高，阴性症状和思想障碍与功能水平较低相关。结论接受治疗的精神分裂症患者继续出现症状。消极症状是最主要的。使用氯氮平的患者的精神病理学水平较高。负面症状和思想障碍的程度与机能水平显着相关。 DOI：http：//dx.doi.org/10.4038/sljpsyc.v2i1.3162 SL J Psychiatry 2011; 2（1）：23-27

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