• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Pain research & management: the journal of the Canadian Pain Society = journal de la socie?te? canadienne pour le traitement de la douleur >Improved Analgesic Effect of Paravertebral Blocks before and after Video-Assisted Thoracic Surgery: A Prospective, Double-Blinded, Randomized Controlled Trial
【24h】

Improved Analgesic Effect of Paravertebral Blocks before and after Video-Assisted Thoracic Surgery: A Prospective, Double-Blinded, Randomized Controlled Trial

机译：电视胸腔镜手术前后椎旁阻滞的改善镇痛效果：一项前瞻性，双盲，随机对照试验

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Despite being less invasive, patients who underwent video-assisted thoracic surgery (VATS) suffered considerable postoperative pain. Paravertebral block (PVB) was proven to provide effective analgesia in patients with VATS; however, there is no difference in pain relief between preoperative PVB and postoperative PVB. This study was aimed to investigate the analgesic efficacy of combination of preoperative and postoperative PVB on the same patient undergoing VATS. In this prospective, double-blinded, randomized controlled trial, 44 patients undergoing VATS were enrolled, and they received patient-controlled intravenous analgesia (PCIA) with sufentanil plus preoperative PVB (Group A, n?=?15) or postoperative PVB (Group B, n?=?15), or combination of preoperative and postoperative PVB (Group C, n?=?14). The primary outcome was sufentanil consumption and PCIA press times in the first 24 hours postoperatively. Also, data of postoperative use of PCIA and visual analogue scale (VAS) were collected. In the first 24 hours postoperatively, median sufentanil consumption in Group C was 0 (0–34.75) μg, which was much less than that in Group A (45.00 (33.00–47.00) μg, ) and Group B (36 (20.00–50.00) μg, ). Patients in Group C pressed less times of PCIA (0 (0–0) times) than patients in Group A (2 (1–6) times, ) and Group B (2 (1–3) times, ). Kaplan–Meier analysis showed patients with combination of preoperative and postoperative PVB had a higher PCIA-free rate than patients with either technique alone (). The VAS among the three groups was comparable postoperatively. The combination of both preoperative and postoperative PVB provides better analgesic efficacy during the early postoperative period and may be an alternative option for pain control after VATS. This trial is registered with ChiCTR1800017102.
机译：尽管侵入性较小，但是接受电视胸腔镜手术（VATS）的患者仍遭受相当大的术后疼痛。椎旁阻滞（PVB）被证明可为VATS患者提供有效的镇痛作用;但是，术前PVB与术后PVB之间的疼痛缓解没有差异。本研究旨在探讨术前和术后联合应用PVB对同一名接受VATS的患者的镇痛效果。在这项前瞻性，双盲，随机对照试验中，纳入了接受VATS的44例患者，他们接受了舒芬太尼联合术前PVB（A组，n = 15）或术后PVB（组）的患者自控静脉镇痛（PCIA）。 B，n？=？15），或术前和术后PVB的组合（C组，n？=？14）。主要结果是术后头24小时服用舒芬太尼和PCIA按压时间。另外，还收集了术后PCIA和视觉模拟量表（VAS）的使用数据。术后头24小时，C组舒芬太尼的中位摄入量为0（0-34.75）μg，远低于A组（45.00（33.00-47.00）μg）和B组（36（20.00-50.00） ）μg，）。 C组患者的PCIA按压次数（0（0-0）次）少于A组（2（1-6）倍）和B组（2（1-3）次）。 Kaplan–Meier分析显示，术前和术后PVB合并的患者比单独使用任何一种技术的患者具有更高的PCIA无发生率（）。三组间的VAS术后相当。术前和术后PVB的组合在术后早期提供了更好的镇痛效果，可能是VATS后疼痛控制的替代选择。该试用版已在ChiCTR1800017102中注册。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号