...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Patient Preference and Adherence >Tolerability, safety and adherence to treatment with insulin detemir injection in the treatment of type 2 diabetes
【24h】

Tolerability, safety and adherence to treatment with insulin detemir injection in the treatment of type 2 diabetes

机译：地特胰岛素注射液治疗2型糖尿病的耐受性，安全性和坚持治疗

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Abstract: The progressive nature of type 2 diabetes poses challenges in the clinic: treatment must be continually reviewed and adjusted in response to the patient’s changing pathophysiology. Ultimately, insulin replacement therapy will be necessary as the physiological insulin response is compromised. The modern basal insulin analog insulin detemir has been the subject of several clinical trials and observational studies in type 2 diabetes. Compared with NPH insulin, insulin detemir offers an improved balance between achieving current glycemic targets with acceptable tolerability. Insulin detemir also has a unique weight-sparing effect which is associated with body mass index, and this may be a particular advantage to obese patients with type 2 diabetes. This review summarizes data from key clinical studies of insulin detemir, and also provides insights from observational studies.
机译：摘要：2型糖尿病的进行性给临床带来了挑战：必须根据患者不断变化的病理生理状况不断对其进行检查和调整治疗。最终，由于生理胰岛素反应受到损害，必须进行胰岛素替代治疗。现代的基础胰岛素类似物地特胰岛素已经成为2型糖尿病的多项临床试验和观察性研究的主题。与NPH胰岛素相比，地特美胰岛素在达到目前的血糖目标和可接受的耐受性之间提供了更好的平衡。德特米尔胰岛素还具有与体重指数相关的独特的减重功效，这对于肥胖的2型糖尿病患者可能是一个特别的优势。这篇综述总结了胰岛素德特米尔关键临床研究的数据，并提供了观察性研究的见解。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号