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首页> 外文期刊>Patient Preference and Adherence >Beliefs that influence cost-related medication non-adherence among the “haves” and “have nots” with chronic diseases
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Beliefs that influence cost-related medication non-adherence among the “haves” and “have nots” with chronic diseases

机译：影响慢性病“有”和“无”的与费用相关的药物依从性的信念

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Background and objective: Some patients continue taking their medication as prescribed despite serious financial pressures, while others with the ability to pay forego treatment due to cost concerns. The primary goal of this study was to explore how patients' beliefs about the necessity of treatment and treatment side effects, influence cost-related non-adherence (CRN).Methods: 27,302 participants in the Harris Interactive Chronic Illness Panel completed an internet survey. The current study focused on two subsamples representing: (a) the most economically-vulnerable survey respondents (ie, individuals with household incomes of US$25,000 per year or less and monthly out-of-pocket medication costs of at least US$60, n = 1321); and (b) respondents who were the most likely to have the financial resources to pay for medications (ie, those with incomes of US$125,000 or more and monthly medication costs of less than US$60.00, n = 1195). Multivariate models were constructed for each group to determine the independent impact on CRN of perceived need for medications and side-effect concerns. Increased risk for CRN associated with depression and asthma diagnoses also was examined.Results: Twenty-one percent of economically vulnerable respondents reported continuing to take their medication as prescribed despite serious cost pressures, while 14% of high-income respondents reported CRN despite apparently manageable out-of-pocket costs. Both low perceived need for medications and concerns about side-effects affected CRN risk in low-income and high-income groups. Within groups of both low-income and high-income respondents, depression and asthma significantly increased patients' odds of reporting CRN.Conclusion: Beyond objective financial measures, CRN is influenced by patient beliefs, which can influence the perceived value of prescription drugs. Addressing these beliefs, as well as the unique adherence concerns of patients with depression and asthma, could decrease CRN rates even if cost pressures themselves cannot be reduced.
机译：背景与目的：尽管有严重的财务压力，一些患者仍继续按处方开药，而另一些患者则出于费用方面的考虑而有能力放弃治疗。这项研究的主要目的是探讨患者对治疗必要性和副作用的看法如何影响费用相关的非依从性（CRN）。方法：Harris交互式慢性疾病小组的27,302名参与者完成了一项互联网调查。当前的研究集中在两个子样本上，这些子样本代表：（a）最经济脆弱的调查受访者（即，家庭年收入在25,000美元或以下，而每月自付费用的药物成本至少为60美元的个人，n = 1321）; （b）最有可能拥有财务资源来支付药物费用的受访者（即，收入为125,000美元或以上且月度药物费用低于60.00美元的患者，n = 1195）。为每个组构建多元模型，以确定感知到的药物需求和副作用问题对CRN的独立影响。结果：与抑郁症和哮喘相关的CRN风险增加。结果：尽管面临巨大的成本压力，经济脆弱的受访者中有21％的人报告继续服用处方药，而高收入受访者中有14％的人报告CRN尽管可以控制。自付费用。在低收入和高收入人群中，对药物的低感知需求和对副作用的担忧都影响了CRN风险。在低收入和高收入受访者群体中，抑郁和哮喘显着增加了患者报告CRN的几率。结论：除了客观的财务指标外，CRN还受患者信念的影响，这可能会影响处方药的感知价值。解决这些信念以及抑郁症和哮喘患者独特的依从性担忧，即使无法降低成本压力，也可能降低CRN率。

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