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Estimation of health state utilities in breast cancer

机译：乳腺癌中健康状态效用的估算

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Purpose: The aim of this study is to determine the utility of breast cancer health states using the standard gamble (SG) and visual analog scale (VAS) methods in the Korean general population. Materials and methods: Eight hypothetical breast cancer health states were developed based on patient education material and previous publications. Data from 509 individuals from the Korean general population were used to evaluate breast cancer health states using the VAS and the SG methods, which were obtained via computer-assisted personal interviews. Mean utility values were calculated for each human papillomavirus (HPV)-related health state. Results: The rank of health states was identical between two valuation methods. SG values were higher than VAS values in all health states. The utility values derived from SG were 0.801 (noninvasive breast cancer with mastectomy and followed by reconstruction), 0.790 (noninvasive breast cancer with mastectomy only), 0.779 (noninvasive breast cancer with breast-conserving surgery and radiation therapy), 0.731 (invasive breast cancer with surgery, radiation therapy, and/or chemotherapy), 0.610 (locally advanced breast cancer with radical mastectomy with radiation therapy), 0.587 (inoperable locally advanced breast cancer), 0.496 (loco-regional recurrent breast cancer), and 0.352 (metastatic breast cancer). Conclusion: Our findings might be useful for economic evaluation of breast cancer screening and interventions in general populations.
机译：目的：本研究旨在确定在韩国普通人群中使用标准赌博（SG）和视觉模拟量表（VAS）方法确定乳腺癌健康状况的效用。材料和方法：根据患者的教育材料和以前的出版物，开发了八个假设的乳腺癌健康状况。来自韩国总人口的509个人的数据被用于通过VAS和SG方法评估乳腺癌的健康状况，这些方法是通过计算机辅助的个人访谈获得的。计算每种人类乳头瘤病毒（HPV）相关健康状态的平均效用值。结果：两种评估方法之间的健康状态等级相同。在所有健康状态下，SG值均高于VAS值。从SG得出的效用值为0.801（无创乳腺癌加乳房切除术然后进行重建），0.790（仅无创乳房癌加乳房切除术），0.779（无创乳腺癌和保留乳房手术及放射疗法），0.731（有创乳腺癌）手术，放射疗法和/或化学疗法治疗），0.610（局部晚期乳腺癌并接受放射治疗的根治性乳房切除术），0.587（无法手术的局部晚期乳腺癌），0.496（局部局部复发性乳腺癌）和0.352（转移性乳腺癌）癌症）。结论：我们的发现可能对普通人群的乳腺癌筛查和干预措施的经济评估有用。

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