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Enhancement of rat lymphatic lipid transport by glucose or amino acids ingestion

机译:葡萄糖或氨基酸摄入增强大鼠淋巴脂质转运

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To elucidate the effect of simultaneously fed carbohydrate or protein on lipid absorption, lymphatic lipid transports in the rat intestine were observed with or without simultaneous feeding of glucose or amino acids. A lipid emulsion containing 40? μ mol/h (35.4?mg/h) of triolein, 2.74? μ mol/h (1.06?mg/h) of cholesterol, 7.8? μ mol/h (6.08?mg/h) of egg phosphatidylcholine without any additive (the Control group), with 560?mmol/h (300?mg/h) of glucose (the Glucose group), or with 400?mmol/h (150?mg/h) of amino acids (the Amino Acids group), was infused intraduodenally at 3?mL/h for 8?h into mesenteric lymph‐fistula rats. The amounts of triglyceride transported in lymph for 8?h were 185?±?12 (mean?±?SE) mg in the Amino Acids group ( n ?=?4), 175?±?3?mg in the Glucose group ( n ?=?5), and 147?±?7?mg in the Control group ( n ?=?4), respectively, with a statistically significant difference ( P ??0.05) among the groups. The amounts of cholesterol transported in lymph for 8?h of the Amino Acid group and the Glucose group seemed to be larger than that of the Control group. The amount of phosphatidylcholine transported in lymph for 8?h were 16.4?±?1.0?mg in the Amino Acids group, 15.7?±?0.4?mg in the Glucose group, and 12.4?±?0.3?mg in the Control group, respectively, with a statistically significant difference ( P ??0.01) among the groups. Simultaneous glucose or amino acids feeding enhanced lymphatic lipid transport in the rat intestine during lipid feeding.
机译:为了阐明同时喂食碳水化合物或蛋白质对脂质吸收的影响,在有或没有同时喂入葡萄糖或氨基酸的情况下,观察了大鼠肠道中淋巴脂质的转运。含有40? μmol / h(35.4?mg / h)的三油精,2.74?胆固醇的微摩尔/小时(1.06?mg / h)7.8?不含任何添加剂的卵磷脂酰胆碱的微摩尔/小时(6.08?mg / h)(对照组),葡萄糖(葡萄糖组)或560?mmol / h(300?mg / h)或400?mmol / h将h(150?mg / h)的氨基酸(“氨基酸”组)以3?mL / h的浓度经十二指肠内注入肠系膜淋巴瘘的大鼠中,持续8?h。氨基酸组(n≥4)的淋巴中甘油三酯的转运量为8?h为185?±?12(平均值?±?SE)mg,葡萄糖组为175?±?3?mg(对照组中的n≥5,和147mg±7mg(n≥4),各组之间的差异有统计学意义(P≤0.05)。氨基酸组和葡萄糖组在淋巴中运输胆固醇达8?h的胆固醇的量似乎大于对照组。在氨基酸组中,淋巴中运送8小时的磷脂酰胆碱的量为16.4±1.0毫克,葡萄糖组为15.7±0.4毫克,对照组为12.4±0.3毫克。各组之间的差异具有统计学意义(P <0.01)。在脂质喂养期间,同时喂养葡萄糖或氨基酸可增强大鼠肠道中淋巴脂质的转运。

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