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首页> 外文期刊>PLOS Neglected Tropical Diseases >Circulation of Japanese Encephalitis Virus in Pigs and Mosquito Vectors within Can Tho City, Vietnam
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Circulation of Japanese Encephalitis Virus in Pigs and Mosquito Vectors within Can Tho City, Vietnam

机译：越南芹T市猪和蚊媒中日本脑炎病毒的传播

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Japanese encephalitis virus (JEV) is a mosquito-borne, zoonotic flavivirus causing encephalitis in humans and reproductive disorder in pigs. JEV is present in large parts of Asia, where urbanization is high. Households within and outside Can Tho city, South Vietnam, were selected to monitor circulation of JEV. A nested RT-PCR was established to detect the presence of JEV in mosquitoes whereas sera from pigs belonging to households within the province were analyzed for the presence of antibodies to JEV. A total of 7885 mosquitoes were collected and divided into 352 pools whereof seven were JEV-positive, six of which were collected within the city. Fragments from four pools clustered with JEV genotype III and three with genotype I. Of the 43 pigs sampled inside the city 100% had JEV antibodies. Our study demonstrates exposure to JEV in pigs, and co-circulation of JEV genotype I and III in mosquitoes within an urban environment in South Vietnam. Thus, although JEV has mainly been considered a rural disease, the potential for transmission in urban areas cannot be ignored.
机译：日本脑炎病毒（JEV）是一种由蚊子传播的人畜共患性黄病毒，可引起人类脑炎和猪繁殖障碍。在城市化程度很高的亚洲大部分地区都存在JEV。越南南部芹T市内外的住户被选为监测JEV的流通。建立了巢式RT-PCR来检测蚊子中是否存在JEV，而对省内一家猪的血清进行了JEV抗体分析。总共收集了7885个蚊子并将其分成352个池，其中7个为JEV阳性，其中6个是在城市内收集的。来自四个池的片段与JEV基因型III聚在一起，三个池与基因型I聚在一起。在城市内采样的43头猪中，有100％具有JEV抗体。我们的研究表明，在越南南部城市环境中，猪暴露于JEV并在蚊子中共同传播JEV基因型I和III。因此，尽管JEV主要被认为是一种农村疾病，但在城市地区传播的可能性不容忽视。

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