• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>PLOS Neglected Tropical Diseases >Sensitivity and Specificity of Multiple Kato-Katz Thick Smears and a Circulating Cathodic Antigen Test for Schistosoma mansoni Diagnosis Pre- and Post-repeated-Praziquantel Treatment
【24h】

Sensitivity and Specificity of Multiple Kato-Katz Thick Smears and a Circulating Cathodic Antigen Test for Schistosoma mansoni Diagnosis Pre- and Post-repeated-Praziquantel Treatment

机译：曼氏血吸虫病多次和多次重复的吡喹酮治疗的敏感性和特异性

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background Two Kato-Katz thick smears (Kato-Katzs) from a single stool are currently recommended for diagnosing Schistosoma mansoni infections to map areas for intervention. This ‘gold standard’ has low sensitivity at low infection intensities. The urine point-of-care circulating cathodic antigen test (POC-CCA) is potentially more sensitive but how accurately they detect S. mansoni after repeated praziquantel treatments, their suitability for measuring drug efficacy and their correlation with egg counts remain to be fully understood. We compared the accuracies of one to six Kato-Katzs and one POC-CCA for the diagnosis of S. mansoni in primary-school children who have received zero to ten praziquantel treatments. We determined the impact each diagnostic approach may have on monitoring and evaluation (M&E) and drug-efficacy findings.
机译：背景技术目前建议从单个粪便上涂两次加藤-卡茨厚涂片（Kato-Katzs），以诊断曼氏血吸虫感染，以绘制区域进行干预。此“金标准”在低感染强度下灵敏度较低。尿液现场即时循环阴极抗原检测（POC-CCA）可能更敏感，但在反复吡喹酮治疗后，它们检测曼氏链球菌的准确性，其用于测量药物功效的适用性以及与卵数的相关性仍有待充分了解。我们比较了接受零至十种吡喹酮治疗的小学生中曼氏葡萄球菌的诊断方法，其中一至六种Kato-Katzs和一种POC-CCA的诊断准确性。我们确定了每种诊断方法可能对监测与评估（M＆E）和药物功效调查结果产生的影响。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号