RNA-Seq Reveals Infection-Induced Gene Expression Changes in the Snail Intermediate Host of the Carcinogenic Liver Fluke, Opisthorchis viverrini

Sattrachai Prasopdee; Javier Sotillo; Smarn Tesana; Thewarach Laha; Jutharat Kulsantiwong; Matthew J. Nolan; Alex Loukas; Cinzia Cantacessi

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RNA-Seq Reveals Infection-Induced Gene Expression Changes in the Snail Intermediate Host of the Carcinogenic Liver Fluke, Opisthorchis viverrini

机译：RNA序列揭示致癌性肝福禄，Ovishorchis viverrini的蜗牛中间宿主中感染诱导的基因表达变化。

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Background Bithynia siamensis goniomphalos is the snail intermediate host of the liver fluke, Opisthorchis viverrini, the leading cause of cholangiocarcinoma (CCA) in the Greater Mekong sub-region of Thailand. Despite the severe public health impact of Opisthorchis-induced CCA, knowledge of the molecular interactions occurring between the parasite and its snail intermediate host is scant. The examination of differences in gene expression profiling between uninfected and O. viverrini-infected B. siamensis goniomphalos could provide clues on fundamental pathways involved in the regulation of snail-parasite interplay.

机译：背景中华按病种Bithynia siamensis goniomphalos是泰国大湄公河次区域胆管癌（CCA）的主要原因，是肝吸虫（Opishorchis viverrini）的蜗牛中间宿主。尽管Opisthorchis诱导的CCA对公共健康造成了严重影响，但对寄生虫与其蜗牛中间宿主之间发生的分子相互作用的了解却很少。检验未感染的和感染O. viverrini的B. siamensis goniomphalos之间的基因表达谱的差异，可以为参与调控蜗牛-寄生虫相互作用的基本途径提供线索。

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《PLOS Neglected Tropical Diseases》 |2014年第3期|共9页
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Sattrachai Prasopdee; Javier Sotillo; Smarn Tesana; Thewarach Laha; Jutharat Kulsantiwong; Matthew J. Nolan; Alex Loukas; Cinzia Cantacessi;
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1. Data set from the proteomic analysis of Bithynia siamensis goniomphalos snails upon infection with the carcinogenic liver fluke Opisthorchis viverrini [J] . Sattrachai Prasopdee, Smarn Tesana, Cinzia Cantacessi, Data in Brief . 2015,第1期

机译：感染致癌性肝吸虫后中华小嘴Bit螺（Bithynia siamensis goniomphalos ）蜗牛的蛋白质组学数据集维氏女贞（Opisthorchis viverrini）
2. Genetic structure and geographical variation of Bithynia siamensis goniomphalos sensu lato (Gastropoda: Bithyniidae), the snail intermediate host of Opisthorchis viverrini sensu lato (Digenea: Opisthorchiidae) in the Lower Mekong Basin revealed by mitochondrial DNA sequences [J] . International Journal for Parasitology . 2020,第1期

机译：Bethynia Siamensis Goniomphalos Sensu Lato（Gastropoda：Bithyniidae），Opisthorchis Viverrini Sensu Lato（Digenea：Opisthorchiidae）的蜗牛中间宿主在线粒体DNA序列显示的下部
3. Opisthorchis viverrini: Gene expression profiling of carcinogenic adult liver fluke worms using 5 ' SAGE [J] . Chutiwitoonchai Nopporn, Shen Yan, Zheng Huajun, Experimental parasitology . 2008,第4期

机译：Opisthorchis viverrini：使用5'SAGE对致癌性成年肝吸虫进行基因表达谱分析
4. Human Intestinal Flukes Haplorchis taichui and Haplorchis pumilio in their Intermediate Hosts, Freshwater Snails Family Thiaridae in Thailand [C] . Krailas D., Dechruksa W., Chotesaengsri S., European Multicolloquium of Parasitology Congress . 2012

机译：人类肠道毛毛绒他中间宿主中的Taichui和Haplorchis Pumilio，淡水蜗牛家庭Thilidae在泰国
5. The role of arthropod second intermediate hosts as avenues for and constraints on the transmission of frog lung flukes (Digenea: Haematoloechidae). [D] . Bolek, Matthew G. 2006

机译：节肢动物第二中间宿主的作用是青蛙肺吸虫传播的途径和限制（Digenea：Haematoloechidae）。
6. RNA-Seq Reveals Infection-Induced Gene Expression Changes in the Snail Intermediate Host of the Carcinogenic Liver Fluke Opisthorchis viverrini [O] . Sattrachai Prasopdee, Javier Sotillo, Smarn Tesana, 2014

机译：RNA序列揭示了致癌性肝吸虫蜗牛中宿主的蜗牛中间宿主中感染诱导的基因表达变化。
7. RNA-seq reveals infection-induced gene expression changes in the snail intermediate host of the carcinogenic liver fluke, Opisthorchis viverrini [O] . Prasopdee, Sattrachai, Sotillo, Javier, Tesana, Smarn, 2014

机译：RNA-seq揭示了致癌性肝吸虫（Opishorchis viverrini）的蜗牛中间宿主中感染诱导的基因表达变化

RNA-Seq Reveals Infection-Induced Gene Expression Changes in the Snail Intermediate Host of the Carcinogenic Liver Fluke, Opisthorchis viverrini

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