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First-episode schizophrenia, bipolar disorder and other psychoses in a rural Irish catchment area: incidence and gender in the Cavan—Monaghan study at 5 years

机译:爱尔兰农村集水区的首发精神分裂症,躁郁症和其他精神病:Cavan-Monaghan研究在5年时的发病率和性别

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Background The potential of first-episode studies in schizophrenia is maximised through systematic epidemiological, clinical and biological comparisons between homogeneous populations of the psychoses. Aims To conduct prolonged accrual of a€?alla€? cases of non-affective and affective psychotic illness on an epidemiologically complete basis. Method Within the region covered by Cavana€”Monaghan psychiatric service (population 102 810), all putative cases of first-episode psychosis were diagnosed using DSMa€”IV. Results From 1995 to 2000, 69 cases of psychosis were ascertained, the incidence being 2.3-fold lower in females than in males. On resolving the a€? corea€? diagnoses of schizophrenia and bipolar disorder, incidence of schizophrenia among women was 7.5-fold lower than among men whereas incidence of bipolar disorder among women was 6.6-fold lower than among men. Conclusions This homogeneous population, which eliminates factors associated with urbanicity and minimises confounding factors such as socio-economic, ethnic and geographical diversity, shows a markedly reduced incidence among females both of schizophrenia and of bipolar disorder.
机译:背景技术通过对精神病同质人群进行系统的流行病学,临床和生物学比较,可以使精神分裂症的首发研究潜力最大化。目的延长应计金额从流行病学的角度来看,非情感性和情感性精神病的病例。方法在卡瓦纳莫纳汉精神病服务所覆盖的地区(人口102 810),所有假定的首发精神病病例均使用DSMA IV诊断。结果从1995年至2000年,确定了69例精神病患者,女性发病率比男性低2.3倍。关于解决? Corea€?诊断为精神分裂症和双相情感障碍时,女性的精神分裂症发病率比男性低7.5倍,而女性的精神分裂症的发病率比男性低6.6倍。结论这一均一的人群消除了与城市化有关的因素,并最小化了诸如社会经济,种族和地理多样性等混杂因素,显示出精神分裂症和双相情感障碍女性的发病率显着降低。

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