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Aggressive incidents in first-episode psychosis

机译:发作性精神病发作事件

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Background Recent research has reported increased risk of aggressive incidents by individuals with psychotic illness. Aims To examine acts of aggression in first-episode psychosis. Method Subjects with a first-episode psychosis were ascertained from a defined catchment area (Nottingham, UK) and reassessed at 3 years ( n =166) using clinical interview, informants, health care and forensic records. Results Of the subjects, 9.6% demonstrated at least one act of serious aggression (defined as weapon use, sexual assault or victim injury) during at least one psychotic episode and 23.5% demonstrated lesser acts of aggression (defined as all other acts of aggression). For all aggressive subjects (33.1%), unemployment (OR=3.6, 95% C11.6-8.0), comorbid substance misuse (OR=3.1, C1 1.1-8.8) and symptoms of overactivity at service contact (OR=6.9,C1 2.7-17.8) had independent effects on risk of aggression. Conclusions We confirmed some previously reported demographic and clinical associations with aggression in first-episode psychosis but no relationship with specific psychotic symptoms or diagnostic groups was observed.
机译:背景技术最近的研究报告说,患有精神病的人发生侵略性事件的风险增加。目的研究发作性精神病的侵略行为。方法从定义的集水区(英国诺丁汉)确定患有首发精神病的受试者,并在3年​​(n = 166)时使用临床访谈,线人,医疗保健和法医记录进行重新评估。结果在至少一次精神病发作期间,受试者中至少有9.6%表现出至少一种严重侵略行为(定义为使用武器,性攻击或受害者受伤),而有23.5%的表现出较少的侵略行为(定义为所有其他侵略行为) 。对于所有攻击性受试者(33.1%),失业(OR = 3.6,95%C11.6-8.0),共病药物滥用(OR = 3.1,C1 1.1-8.8)和服务接触时活动过度的症状(OR = 6.9,C1 2.7-17.8)对侵略风险具有独立影响。结论我们证实了先前报道的人口统计学和临床​​上与发作性精神病相关的关联,但未观察到与特定精神病性症状或诊断组的关系。

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