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Comparison of the outcome and treatment of psychosis in people of Caribbean origin living in the UK and British Whites

机译:比较居住在英国和英国白人中的加勒比血统人群的精神病结局和治疗方法

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Background The comparative outcome of psychosis in British Whites and UK Africana€”Caribbeans is unclear. Some report that Africana€”Caribbeans have worse outcome, whereas others claim better symptomatic outcome and a more benign course. Aims To compare the course, outcome and treatment of psychosis in Africana€”Caribbeans and British Whites in a large multi-centre sample. Method A secondary analysis of 708 patients with research diagnostic criteria-defined psychosis from a 2-year, randomised controlled trial of case management. Outcome measures (hospitalisation, illness course, self-harm, social disability and treatment received) were adjusted for socio-economic and clinical differences between groups at baseline using regression analysis. Results Africana€”Caribbeans were less likely to have a continuous illness and to receive treatment with antidepressant or psychotherapy. Conclusions The outcome of psychosis is complex but differs between UK Africana€”Caribbeans and British Whites. This may reflect risk factors that increase the rate of psychosis in UK Africana€”Caribbeans. Treatment differences require further investigation.
机译:背景尚不清楚英国白人和英国非洲裔加勒比地区精神病的相对结果。有报告称非洲加勒比海地区的结局较差,而另一些人则称其有症状的结局较好,病程更佳。目的在一个大型的多中心样本中,比较非洲裔加勒比海地区和英属白人的精神病病程,结果和治疗。方法从一项为期2年的病例管理随机对照试验中,对708例研究诊断标准定义为精神病的患者进行二次分析。在基线时使用回归分析针对两组之间的社会经济和临床差异对结果指标(住院,病程,自残,社会残疾和接受的治疗)进行了调整。结果非洲人加勒比海患连续性疾病的可能性较小,接受抗抑郁药或心理疗法的可能性较小。结论精神病的结局很复杂,但在英国非洲裔加勒比人和英国白人之间有所不同。这可能反映了风险因素,这些风险因素增加了英国非洲裔加勒比海地区的精神病发病率。治疗差异需要进一步调查。

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