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首页> 外文期刊>The British journal of psychiatry : >Acute and transient psychotic disorders: precursors, epidemiology, course and outcome
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Acute and transient psychotic disorders: precursors, epidemiology, course and outcome

机译：急性和短暂性精神病：前兆，流行病学，病程和结局

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Background ICDa€“10 has introduced the diagnostic group acute and transient psychotic disorders (ATPDs; F23). Aims To validate the nosological distinctiveness of ICDa€“10 ATPDs by following up an inception cohort with first-episode psychosis. Method All patients with first-episode psychosis identified in Nottingham between 1992 and 1994 and diagnosed using ICDa€“10 criteria were reassessed 3 years later. ATPD outcomes were compared with schizophrenia and affective psychosis. Multivariate analyses were conducted to determine whether acute onset and early remission predicted favourable 3-year outcome in first-episode psychosis. Results Of 168 cases of first-episode psychosis, 32 (19%) received an intake diagnosis of ATPD. The diagnosis of ATPD was stable in women over 3 years, but not in men. Outcomes in ATPD were better than in schizophrenia and similar to affective psychosis. In non-affective psychoses, favourable outcomes were a function of gender and premorbid functioning rather than acute onset and early remission. Conclusions The ICDa€“10 criteria for ATPDs identify a diagnostically unstable group of disorders. Acute onset and early remission do not independently predict favourable outcome over 3 years in first-episode psychosis.
机译：背景技术ICDa 10引入了诊断组：急性和短暂性精神病（ATPD; F23）。目的通过随访首发性精神病患者，验证ICDa 10 ATPD的疾病学独特性。方法3年后对1992年至1994年在诺丁汉发现并使用ICDa-10标准诊断出的所有首发精神病患者进行重新评估。将ATPD结果与精神分裂症和情感性精神病进行比较。进行多变量分析以确定急性发作和早期缓解是否预示了首发精神病的3年预后良好。结果168例首次发作的精神病患者中，有32例（19％）接受了ATPD的摄入诊断。女性超过3年的ATPD诊断稳定，而男性则没有。 ATPD的结果优于精神分裂症，与情感性精神病相似。在非情感性精神病患者中，良好的预后取决于性别和病前功能，而不是急性发作和早期缓解。结论ATPD的ICDa 10标准确定了诊断上不稳定的一组疾病。急性发作和早期缓解并不能独立预测首发精神病患者3年内的预后良好。

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