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首页> 外文期刊>The British journal of psychiatry : >Clinical and social determinants of duration of untreated psychosis in the ?SOP first-episode psychosis study
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Clinical and social determinants of duration of untreated psychosis in the ?SOP first-episode psychosis study

机译：？SOP首发精神病研究中未治疗精神病持续时间的临床和社会决定因素

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Background Despite considerable research investigating the relationship between a long duration of untreated psychosis (DUP) and outcomes, there has been much less considering predictors of a long DUP. Aims To investigate the clinical and social determinants of DUP in a large sample of patients with a first episode of psychosis. Method All patients with a first episode of psychosis who made contact with psychiatric services over a 2-year period and were living in defined catchment areas in London and Nottingham, UK were included in the ?? SOP study. Data relating to clinical and social variables and to DUP were collected from patients, relatives and case notes. Results An insidious mode of onset was associated with a substantially longer DUP compared with an acute onset, independent of other factors. Unemployment had a similar, if less strong, effect. Conversely, family involvement in help-seeking was independently associated with a shorter duration. There was weak evidence that durations were longer in London than in Nottingham. Conclusions These findings suggest that DUP is influenced both by aspects of the early clinical course and by the social context.
机译：背景技术尽管有大量研究调查了长期未治疗的精神病（DUP）与预后之间的关系，但是考虑到长期DUP的预测因素却少得多。目的调查大量患有首发精神病的患者样本中DUP的临床和社会决定因素。方法将所有在两年内与精神科服务机构接触并居住在伦敦和英国诺丁汉的特定集水区的首次精神病发作的患者纳入研究范围。 SOP研究。从患者，亲戚和病例记录中收集与临床和社会变量以及DUP相关的数据。结果隐匿性发作模式与DUP相比，与急性发作相比明显更长，与其他因素无关。失业也有类似的影响，即使程度较弱。相反，家庭参与寻求帮助与持续时间较短独立相关。鲜有证据表明伦敦的时间比诺丁汉的时间长。结论这些发现表明，DUP受早期临床过程的各个方面以及社会背景的影响。

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