• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Internet Journal of Academic Physician Assistants >Is there enough evidence to support the use of 17 Alpha-Hydroxyprogesterone Caproate in preventing preterm labor in healthy women who have had a prior preterm delivery?
【24h】

Is there enough evidence to support the use of 17 Alpha-Hydroxyprogesterone Caproate in preventing preterm labor in healthy women who have had a prior preterm delivery?

机译：是否有足够的证据支持使用己酸17-羟孕酮预防健康的早产妇女早产？

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Introduction Preterm birth is defined as spontaneous or medically induced labor prior to the onset of 37 weeks. Currently, preterm birth is the number one cause of neonate mortality and can lead to morbidities such as cerebral palsy, heart defects, chronic lung diseases, and neurological deficits. Currently, it is unknown why some women experience preterm labor while others are unaffected. It is clear through numerous studies that many factors can contribute to preterm birth such as race, socioeconomic factors, uterine infections, and uterine abnormalities. There have been trials conducted to see if giving 17 Alpha-Hydroxyprogesterone Caproate (17P) will decrease the incidence of preterm births. It is thought that since 17P is an active metabolite of progesterone that it will have the same properties as progesterone such as relaxing smooth muscle, blocking the action of oxytocin, and inhibiting formation of gap junctions resulting in prevention of preterm birth. Therefore, it is important to researchers and physicians to find out how to prevent preterm births to decrease the mortality, morbidities, and costs associated with caring for preterm infants.
机译：简介早产定义为发病37周之前的自然或医学引产。当前，早产是导致新生儿死亡的第一大原因，并可导致诸如脑瘫，心脏缺陷，慢性肺部疾病和神经系统缺陷等疾病。目前，尚不清楚为什么有些妇女经历早产而另一些妇女不受影响。通过大量研究清楚地表明，许多因素可导致早产，例如种族，社会经济因素，子宫感染和子宫异常。已经进行了一些试验，看是否给予17己酸α-羟孕酮（17P）可以降低早产的发生率。据认为，由于17P是孕酮的活性代谢物，因此其具有与孕酮相同的性质，例如松弛平滑肌，阻断催产素的作用，抑制间隙连接的形成，从而导致防止早产。因此，对于研究人员和医生来说，重要的是找出如何预防早产以降低与照顾早产儿有关的死亡率，发病率和成本。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号