• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Open Crystallography Journal >X-Ray Crystal Structures of a 1-(p-fluorophenyl)-2-(α-pyridyl)ethanol Intermediate and the 1-(p-fluorophenyl)-2-(α-pyridyl)ethene Dehydration Compound Obtained from the Condensation Reaction of 2-Methylpyridine and p-Fluorobenzaldehyde
【24h】

X-Ray Crystal Structures of a 1-(p-fluorophenyl)-2-(α-pyridyl)ethanol Intermediate and the 1-(p-fluorophenyl)-2-(α-pyridyl)ethene Dehydration Compound Obtained from the Condensation Reaction of 2-Methylpyridine and p-Fluorobenzaldehyde

机译：从（1-氟苯基）-2-（α-吡啶基）乙醇中间体与1-（对氟苯基）-2-（α-吡啶基）乙烯脱水化合物的缩合反应获得的X射线晶体结构2-甲基吡啶和对氟苯甲醛

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The compound 1-(p-fluorophenyl)-2-(p-pyridyl)ethanol and its corresponding dehydration compound 1-(pfluorophenyl)-2-(p-pyridyl)ethene were obtained from the Knoevenagel condensation reaction between 2-methylpyridinewith p-fluorobenzaldehyde. The X-ray structure determined for 1-(p-fluorophenyl)-2-(p-pyridyl)ethanol reveals that thecompound crystallizes in the monoclinic system space group, P21, containing four molecules in each crystal unit cell [a= 5.3664(15) ?, b = 8.343(2) ?, c = 25.056(6) ?, and β = 93.837(15)°]. The crystal structure shows the formation of anintermolecular hydrogen bond O-H…N between the oxygen atom of the O–H and the nitrogen atom of a pyridine group ofthe next molecule. The condensation product 1-(p-fluorophenyl)-2-(2-pyridyl)ethene crystallizes in the monoclinic system,in the Cc space group, with unit cell dimensions a = 22.920(7) ?, b = 5.9149(14) ?, c = 7.8544(15) ?, and β =104.16(2)°. The molecular structure shows the p-fluorophenyl ring attached to the double bond and located trans to thepyridine ring. The crystallography data give evidence that the intermediary compound is actually the alcohol just beforethe dehydration process that yields the trans double bond of the 1-(p-fluorophenyl)-2-(p-pyridyl)ethene.
机译：化合物1-（对氟苯基）-2-（对吡啶基）乙醇及其相应的脱水化合物1-（对氟苯基）-2-（对吡啶基）乙烯是由2-甲基吡啶与对羟基苯甲酸酯之间的Knoevenagel缩合反应制得的。氟苯甲醛。测定的1-（对氟苯基）-2-（对吡啶基）乙醇的X射线结构表明，该化合物在单斜晶系空间群P21 / n中结晶，每个晶体晶胞中均含有四个分子[a = 5.3664 （15）θ，b ＝ 8.343（2）θ，c ＝ 25.056（6）θ，β＝ 93.837（15）°]。晶体结构显示了O–H的氧原子与下一个分子的吡啶基的氮原子之间的分子间氢键O-H…N的形成。缩合产物1-（对氟苯基）-2-（2-吡啶基）乙烯在Cc空间群的单斜晶系中结晶，晶胞尺寸a = 22.920（7）?， b = 5.9149（14）?。 ，c ＝ 7.8544（15）°，β＝ 104.16（2）°。分子结构显示对-氟苯基环连接至双键并反式定位于吡啶环。晶体学数据提供了证据，表明中间体化合物实际上是在脱水过程之前的醇，该脱水过程产生了1-（对氟苯基）-2-（对吡啶基）乙烯的反式双键。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号