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From manual curation to visualization of gene families and networks across Solanaceae plant species

机译：从人工策划到茄科植物物种基因家族和网络的可视化

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High-quality manual annotation methods and practices need to be scaled to the increased rate of genomic data production. Curation based on gene families and gene networks is one approach that can significantly increase both curation efficiency and quality. The Sol Genomics Network (SGN; http://solgenomics.net) is a comparative genomics platform, with genetic, genomic and phenotypic information of the Solanaceae family and its closely related species that incorporates a community-based gene and phenotype curation system. In this article, we describe a manual curation system for gene families aimed at facilitating curation, querying and visualization of gene interaction patterns underlying complex biological processes, including an interface for efficiently capturing information from experiments with large data sets reported in the literature. Well-annotated multigene families are useful for further exploration of genome organization and gene evolution across species. As an example, we illustrate the system with the multigene transcription factor families, WRKY and Small Auxin Up-regulated RNA (SAUR), which both play important roles in responding to abiotic stresses in plants. Database URL: http://solgenomics.net/
机译：需要调整高质量的手动注释方法和实践，以提高基因组数据产生的速度。基于基因家族和基因网络的策展是一种可以显着提高策展效率和质量的方法。 Sol Genomics Network（SGN; http://solgenomics.net）是一个比较基因组学平台，具有茄科及其紧密相关物种的遗传，基因组和表型信息，并结合了基于社区的基因和表型管理系统。在本文中，我们描述了一种用于基因家族的手动管理系统，旨在促进复杂生物过程基础的基因相互作用模式的管理，查询和可视化，包括一个接口，该接口可有效地从文献中报道的大型数据集中捕获信息。注释明确的多基因家族对于进一步探索物种间的基因组组织和基因进化很有用。例如，我们说明了具有多基因转录因子家族WRKY和Small Auxin上调RNA（SAUR）的系统，它们在响应植物中的非生物胁迫方面均起着重要作用。数据库网址：http://solgenomics.net/

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