N-alkylation of azoles disubstituted acetamides under microwave and Mannich reaction conditions

Ambarsing P. Rajput; Rambhau P. Gore

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N-alkylation of azoles disubstituted acetamides under microwave and Mannich reaction conditions

机译：微波和曼尼希反应条件下唑类二取代乙酰胺的N-烷基化

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The N-alkylation of some secondary amides, 2-(1H-azol-1-yl)-N-(substituted phenyl) acetamides, was carried out under different conditions basic, microwave and Mannich reaction. The attempts of alkylation of secondary amides using strong bases were unsuccessful. These prompted us to apply microwave and Mannich reaction.

机译：在碱性，微波和曼尼希反应的不同条件下，进行了一些仲酰胺（2-（1H-唑-1-基）-N-（取代的苯基）乙酰胺）的N-烷基化反应。使用强碱将仲酰胺烷基化的尝试未成功。这些促使我们应用微波和曼尼希反应。

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《Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry》 |2012年第6期|共6页
作者
Ambarsing P. Rajput; Rambhau P. Gore;
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N-alkylation of azoles disubstituted acetamides under microwave and Mannich reaction conditions

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