One-pot multicomponent synthesis and antibacterial evaluation of some novel acridine derivatives

Baseer M Shaikh; Shankaraiah G. Konda; Atul V. Mehare; Gajanan G. M; awad; Santosh S . Chobe; Bhaskar S. Dawane

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One-pot multicomponent synthesis and antibacterial evaluation of some novel acridine derivatives

机译：一锅多组分合成和一些新型novel啶衍生物的抗菌性能

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In the present communication a simple and efficient synthesis of some new acridines are described by the one-pot condensation of 3, 4, 9, 10-tetrahydroacridine-1(2H)-one, substituted aldehyde and liquior ammonia in alkaline polyethylene glycol (PEG-400) as green reaction solvent. The newly synthesized products were evaluated for their antibacterial and antifungal activity.

机译：在本通讯中，通过在碱性聚乙二醇（PEG）中一锅缩合3、4、9、10-四氢ac啶-1（2H）-1，取代的醛和液态氨来描述一些新的a啶的简单有效的合成方法-400）作为绿色反应溶剂。评价新合成的产品的抗菌和抗真菌活性。

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《Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry》 |2010年第4期|共5页
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Baseer M Shaikh; Shankaraiah G. Konda; Atul V. Mehare; Gajanan G. M; awad; Santosh S . Chobe; Bhaskar S. Dawane;
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One-pot multicomponent synthesis and antibacterial evaluation of some novel acridine derivatives

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