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首页> 外文期刊>Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry >Effect of polar and nonpolar solvent on total phenolic and antioxidant activity of roots extracts of Caralluma europaea
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Effect of polar and nonpolar solvent on total phenolic and antioxidant activity of roots extracts of Caralluma europaea

机译：极性和非极性溶剂对欧洲榄香根提取物总酚和抗氧化活性的影响

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摘要

Caralluma europaea have been used recently as a remedy in Morocco folk medicine, health foods and in numerous other purposes. In the present study, the antioxidant activity of C. Europaea roots extracts from morocco cultivar Zouiatcheikh harvested, using solvents of increasing polarity (hexane, chloroform, dichloromethane, ethyl acetate, acetone, ethanol and methanol) was evaluated using DPPH radical-scavenging assay. The total ascorbic acid, pigment and anthocyanins as well as total phenolics and flavonoids from roots of C. Europaea cultivar were also evaluated. The extracts were found to have different levels in antioxidant proprieties in the test solvent used. The efficiency of the solvents used to extract phenolic compounds from the C. Europaea roots varied considerably. Total polyphenol contents were significantly higher in methanol extract than chloroform and ethanol fractions (p0.05). Ethanol and ethyl acetate extracts in roots was found to be rich in flavonoids (834.7 and 844.2 CEQ/100g DW, respectively). No relationship was observed in the potential antioxidant activity and total phenolic levels of the extracts mean that further investigation on the antioxidant activity of C. Europaea roots was needed.
机译：Caralluma europaea最近已被用作摩洛哥民间医学，保健食品和许多其他用途的药物。在本研究中，使用DPPH自由基清除法评估了极性不断增加的溶剂（己烷，氯仿，二氯甲烷，乙酸乙酯，丙酮，乙醇和甲醇）中所收获的摩洛哥品种Zouiatcheikh的欧洲油桐根提取物的抗氧化活性。还评估了欧洲念珠菌根的总抗坏血酸，色素和花青素以及总酚和类黄酮。发现提取物在使用的测试溶剂中具有不同水平的抗氧化剂特性。从欧洲油茶根中提取酚类化合物所用溶剂的效率差异很大。甲醇提取物中的总多酚含量显着高于氯仿和乙醇馏分（p <0.05）。发现根中的乙醇和乙酸乙酯提取物富含类黄酮（分别为834.7和844.2 CEQ / 100g DW）。没有观察到潜在的抗氧化活性和提取物中总酚水平的关系，这意味着需要进一步研究欧洲油菜根的抗氧化活性。

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