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首页> 外文期刊>The Egyptian Journal of Neurology, Psychiatry and Neurosurgery >Diabetic Polyneuropathy versus Diabetic Chronic Inflammatory Demyelinating Polyneuropathy; Clinical, Laboratory and Electrophysiological Study
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Diabetic Polyneuropathy versus Diabetic Chronic Inflammatory Demyelinating Polyneuropathy; Clinical, Laboratory and Electrophysiological Study

机译：糖尿病性多发性神经病与糖尿病性慢性炎性脱髓鞘性多发性神经病;临床，实验室和电生理研究

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Background: The most common type of diabetic neuropathy is symmetrical distal mainly sensory polyneuropathy, but we recognize a type of neuropathy similar to chronic inflammatory demyelinating polyneuropathy (CIDP) occurring in diabetics. Objective: Study clinical, electrophysiological and laboratories clues to differentiate between diabetic neuropathy and CIDP like syndrome. Methods: Group A, include 26 patients (16 male and 10 female) with mean age 54.5±7.3 had diabetic polyneuropathy. Group B, include 9 diabetic patients with CIDP like syndrome (6 male and 3 female) with mean age 58.5±8.6. Motor nerve conduction study of median, ulnar, tibial and peroneal nerves, sensory nerve conduction study of median, ulnar and sural nerves were examined. F-waves of median, ulnar, tibial and peroneal nerves were calculated. Lumber puncture was done for cerebrospinal fluid protein level. Results: Group A showed 61.5% of patients had progressive sensory motor neuropathy while 88.8% in group B showed subacute motor neuropathy. There were significant differences between two groups as regard DML, MNCV, and F-wave (P-values were 0.001, 0.008 and 0.001 respectively). There was no significant difference as regard non-recordable compound muscle action potential (CMAP) between two groups. Conduction block was present in 80% of patients with CIDP like neuropathy (P=0.001). There was significant elevation of CSF proteins in patient with CIDP like neuropathy. Conclusion; There is type of neuropathy developed in diabetics had the following characters, subacute onset, progressive weakness with electrophysiological findings of demyelination and elevation of CSF protein. [Egypt J Neurol Psychiat Neurosurg.  2015; 52(1): 15-19]
机译：背景：糖尿病性神经病的最常见类型是对称性远端远端感觉神经性多发性神经病，但我们认识到一种类似于糖尿病患者的慢性炎症性脱髓鞘性多发性神经病（CIDP）的神经病。目的：研究临床，电生理和实验室线索以区分糖尿病性神经病和CIDP样综合征。方法：A组包括26例平均年龄54.5±7.3岁的糖尿病多发性神经病患者（男16例，女10例）。 B组包括9例患有CIDP综合征的糖尿病患者（男6例，女3例），平均年龄58.5±8.6。检查了正中，尺，胫，腓神经的运动神经传导研究，正中，尺和腓肠神经的感觉神经传导研究。计算了正中，尺骨，胫骨和腓神经的F波。进行腰椎穿刺以检查脑脊液蛋白水平。结果：A组显示61.5％的患者患有进行性感觉运动神经病，而B组的88.8％患者表现为亚急性运动神经病。两组之间在DML，MNCV和F波方面存在显着差异（P值分别为0.001、0.008和0.001）。两组之间在不可记录的复合肌肉动作电位（CMAP）方面无显着差异。在80％的CIDP患者中存在传导阻滞，如神经病变（P = 0.001）。 CIDP患者如神经病患者的CSF蛋白显着升高。结论;糖尿病患者出现的一种神经病具有以下特征：亚急性发作，进行性肌无力以及脱髓鞘的电生理学发现和CSF蛋白升高。 [埃及J Neurol精神病神经外科。 2015; 52（1）：15-19]

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