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Percutaneous Transluminal Angioscopy During Coronary Intervention

机译:冠状动脉介入治疗中的经皮腔内血管镜检查

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To investigate the feasibility of angioscopic-guided percutaneoustransluminal coronary angioplasty and to elucidate the mechanismof efficacy of coronary stenting for acute myocardial infarction,we performed coronary angioscopy in 102 patients with stableangina or acute myocardial infarction. Thrombi and intimal flapswere observed in most patients after coronary angioplasty. Largeintimal splits were seen in one third of patients. Stents wereinserted in 10 patients who were revealed to have a large flap orprotruding split to the inner lumen. Thrombolytic agents wereadministered in 2 patients with large thrombi. Additionaltreatments were required in 32% of patients. No acutemyocardial infarction or unstable angina occurred in patientsduring hospitalization. Thus, angioscopy of the coronary lumenenables clinicians to determine the most appropriate and leastrisky coronary intervention strategy. In patients with acutemyocardial infarction, angioscopy revealed occlusive or protrudingthrombi in 34 of 35 patients. The protruding thrombi disappearedafter stenting. The frequency of large intimal flaps increasedafter predilatation with balloon, but these disappeared afterstenting. The present angioscopic study demonstrates that thecoronary stent compresses the occlusive or protruding thrombi andcovers the ruptured thrombogenic plaque Consequently,smooth-surfaced and wide vessel lumen are obtained.
机译:为了研究经血管镜引导的经皮腔内冠状动脉成形术的可行性,并阐明冠状动脉支架置入术对急性心肌梗死的疗效机制,我们对102例稳定型心绞痛或急性心肌梗死患者进行了冠状动脉造影。大多数患者在冠状动脉成形术后均观察到血栓和内膜瓣。在三分之一的患者中看到较大的内膜裂痕。在发现有大皮瓣或向内腔突出的10名患者中插入了支架。 2名大血栓患者使用了溶栓剂。 32%的患者需要额外的治疗。住院期间未发生急性心肌梗塞或不稳定型心绞痛。因此,对冠状动脉可通透性临床医生进行血管镜检查,以确定最合适和最低风险的冠状动脉介入治疗策略。在患有急性心肌梗塞的患者中,35例患者中有34例的血管造影显示了闭塞性或突出性血栓。支架置入后,突出的血栓消失。气囊扩张后大内膜瓣的发生频率增加,但在支架置入后消失。目前的血管镜研究表明,冠状动脉支架可压缩闭塞性或突出性血栓并覆盖破裂的血栓形成斑块。因此,可获得平滑且宽阔的血管腔。

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