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首页> 外文期刊>JA Clinical Reports >The effect of labor epidural analgesia on labor, delivery, and neonatal outcomes: a propensity score-matched analysis in a single Japanese institute
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The effect of labor epidural analgesia on labor, delivery, and neonatal outcomes: a propensity score-matched analysis in a single Japanese institute

机译：硬膜外分娩镇痛对分娩，分娩和新生儿结局的影响：在一家日本机构中的倾向得分匹配分析

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Abstract PurposeLumbar epidural analgesia (LEA) is the most widely used method in reducing labor pain. Previous RCTs have shown that LEA does not increase cesarean section rates; however, the results are inconsistent and may vary depending on the different backgrounds. Therefore, we aimed to study whether LEA would affect the course of labor in our institute.MethodsDelivery records from October 2013 to April 2016 were collected. Deliveries at gestational age ?36?weeks and multiple pregnancies were excluded. All cases were divided into the non-epidural labor (NEL) group or the epidural labor (EL) group. We performed a propensity score matching analysis to balance intergroup differences. Our primary outcome was a mode of delivery (spontaneous, assisted vaginal, cesarean). Secondary outcomes were lengths of labor and outcomes of the neonates.ResultsDuring the study period, 2632 cases met the inclusion criteria. All analyses were performed after propensity score matching (218 pairs). The percentage of assisted vaginal delivery increased by the use of LEA (11.5% in NEL group vs 25.7% in EL group; p ?0.001), but the rate of cesarean section was similar (12.8% vs 17.0%; p =?0.23). The durations of the first and second stages of labor were prolonged by the use of LEA in both primipara and multipara women. Outcomes of the neonates were similar in both groups.ConclusionUse of LEA did not increase the rate of cesarean section when analyzed by propensity score-matched analysis in our institute.
机译：摘要目的腰椎硬膜外镇痛（LEA）是减轻劳动疼痛的最广泛使用的方法。先前的RCT显示，LEA并不会增加剖宫产率。但是，结果不一致，并且可能因背景不同而有所差异。因此，我们旨在研究LEA是否会影响我们研究所的工作过程。方法收集了2013年10月至2016年4月的交付记录。胎龄＜36周时分娩和多胎妊娠被排除在外。所有病例均分为非硬膜外分娩（NEL）组或硬膜外分娩（EL）组。我们进行了倾向得分匹配分析，以平衡组间差异。我们的主要结局是分娩方式（自发，辅助阴道，剖宫产）。次要结局为分娩时长和新生儿结局。结果在研究期间，有2632例符合纳入标准。所有分析均在倾向得分匹配（218对）之后进行。使用LEA有助于阴道分娩的百分比增加（NEL组为11.5％，EL组为25.7％; p <？0.001），但剖宫产率相似（12.8％vs 17.0％; p =？0.23） ）。初产妇和多产妇均使用LEA延长了第一和第二产程的时间。两组新生儿的结果相似。结论在本研究所通过倾向得分匹配分析进行分析时，使用LEA并不会增加剖宫产率。

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