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首页> 外文期刊>Journal of AIDS and HIV Research >Prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) co-infections among HIV infected people in Iran
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Prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) co-infections among HIV infected people in Iran

机译:伊朗感染艾滋病毒的人中乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)合并感染的患病率

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Infections of human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV) are among the grave health concerns confronting global public health. These infections spread via similar routes (e.g. parenteral, sexual and vertical); leading to the anticipation of high prevalence rates of HBV and HCV co-infections among HIV infected patients. HBV and HCV co-infections in HIV-positive patients lead to severe liver disease by means of rapid progression to hepatocellular carcinoma and severe chronic hepatitis. Consequently, the co-infection of these viruses is strongly associated with reduced survival of HIV patients. Various studies have been conducted among Iranian HIV-positive patients to identify HBV/HIV, HCV/HIV and HBV/HCV/HIV co-infection prevalence rates and their correlations. These surveys have been conducted in many cities and a variety of settings throughout the country. These studies have shown that the alarming high rates of HBV/HCV co-infection among HIV patients highlight the need for a timely and systematic assessment of these patients. It is evident that early diagnosis and early start of appropriate treatments could increase the length of life for co-infected HIV patients; therefore, comprehensive identification of risk factors and underlying conditions, as well as HIV treatment, are highly recommended to prevent HBV/HCV co-infection among HIV-positive patients.
机译:人类免疫缺陷病毒(HIV),乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)的感染是全球公共卫生面临的严重健康问题。这些感染通过类似途径传播(例如,肠胃外,性和垂直感染);导致人们期望HIV感染患者中HBV和HCV合并感染的发生率很高。 HIV阳性患者的HBV和HCV合并感染会通过迅速发展为肝细胞癌和严重的慢性肝炎而导致严重的肝脏疾病。因此,这些病毒的共感染与HIV患者的存活率降低密切相关。在伊朗HIV阳性患者中进行了各种研究,以鉴定HBV / HIV,HCV / HIV和HBV / HCV / HIV合并感染的发生率及其相关性。这些调查已在全国许多城市和各种环境中进行。这些研究表明,艾滋病毒患者中令人震惊的HBV / HCV合并感染率很高,这表明需要对这些患者进行及时,系统的评估。显然,早期诊断和尽早开始适当的治疗可以增加合并感染HIV患者的寿命。因此,强烈建议全面识别危险因素和潜在疾病以及进行HIV治疗,以防止HIV阳性患者中HBV / HCV合并感染。

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