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首页> 外文期刊>Journal of Bangladesh College of Physicians and Surgeons >Impact of Seminal Plasma Zinc and Serum Zinc Level on Semen Parameter of Fertile and Infertile Males
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Impact of Seminal Plasma Zinc and Serum Zinc Level on Semen Parameter of Fertile and Infertile Males

机译:精浆锌和血清锌水平对可育和不育男性精液参数的影响

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Background: Despite Zinc (Zn) deficiency being prevalent in humans, less emphasis has been given on the understanding of its impact on male reproduction. Spermatogenesis has a strict requirement for zinc. The relationship of seminal plasma zinc level and semen parameter until now is controversial .Objective : The study was done to find out the impact of seminal plasma zinc and serum zinc level on semen parameter of fertile and infertile males.Subjects and methods: The study was done in Center for Assisted Reproduction, a tertiary Infertility center in Dhaka and in the Biochemistry Department of Bangabandhu Sheik Mujib Medical University (BSMMU), Dhaka. Sixteen fertile males were taken as control and sixty nine infertile males were taken as cases. Semen analysis was done according to WHO criteria (.2004). Serum zinc and seminal plasma zinc levels were measured in the Biochemistry Department of BSMMU by Graphite Furnace Atomic Absorption Spectrophotometer.Result: Seminal parameters between fertile and infertile men showed significantly high sperm count, sperm motility, rapid linear motility, and morphology in fertile group. In fertile men, serum zinc level was lower than the infertile group, whereas the seminal plasma zinc level was higher in the fertile than the infertile group which was not statistically significant. In fertile men except for serum zinc, all parameters showed positive relationship; and in infertile men, except sperm morphology, all other parameters showed negative relationship. Seminal plasma zinc shows positive correlation with all semen parameters in fertile group and negative correlation in infertile group except for sperm morphology. There is negative correlation of serum zinc and seminal zinc-in both groups. Regarding other parameters, semen zinc shows positive correlation with all parameter except sperm morphology in fertile men and negative correlation with all parameter except sperm count in infertile men.Conclusion: Seminal zinc levels in fertile men are higher than those in the infertile patients although the serum zinc level is lower. Zinc levels in seminal plasma has a direct relationship with semen parameters. Zinc deficiency may be an important risk factor for low semen parameters and idiopathic male infertility.J Bangladesh Coll Phys Surg 2017; 35(1): 15-19
机译:背景:尽管锌(Zn)缺乏症在人类中很普遍,但人们对锌对男性生殖的影响的了解却很少。精子生成对锌有严格的要求。迄今为止,精液血浆锌水平与精液参数之间的关系还存在争议。目的:进行研究以了解精浆血浆锌和血清锌水平对可育和不育男性精液参数的影响。在达卡的三级不育中心辅助生殖中心和达卡的班加班德酋长穆吉布医科大学(BSMMU)的生物化学系完成。以十六名可育男性为对照,以六十九名不育男性为例。精液分析是根据WHO标准(.2004)进行的。用石墨炉原子吸收分光光度计在BSMMU生化科测量血清锌和精浆血浆锌水平。在可育男性中,血清锌水平低于不育组,而可育者的精浆血浆锌水平高于不育组,这在统计学上无统计学意义。除血清锌外,在可育男性中,所有参数均呈正相关。在不育男性中,除了精子形态外,其他所有参数均呈负相关。除精子形态外,精浆中精液锌与所有精液参数呈正相关,不育组与精液中的锌呈负相关。两组的血清锌和精液锌呈负相关。在其他参数方面,不育男性精子锌与除精子形态外的所有参数呈正相关,与不育男性除精子计数外的其他所有参数呈负相关。结论:尽管血清锌含量较低。精浆中的锌水平与精液参数有直接关系。锌缺乏可能是导致精液参数低和特发性男性不育的重要危险因素.J Bangladesh Coll Phys Surg 2017; 35(1):15-19

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