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首页> 外文期刊>Journal of Cancer Research and Therapeutics >A correlative study of solitary thyroid nodules using the bethesda system for reporting thyroid cytopathology
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A correlative study of solitary thyroid nodules using the bethesda system for reporting thyroid cytopathology

机译：使用Bethesda系统报告甲状腺细胞病理学的孤立性甲状腺结节的相关研究

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Background: Fine needle aspiration cytology (FNAC) is a useful diagnostic modality in the evaluation of solitary thyroid nodules (STN). It can differentiate between benign and malignant lesions in most cases. Aim: This study was undertaken to determine the utility and diagnostic accuracy of FNAC in the evaluation of STN. Materials and Methods: In this retrospective study, a total number of 483 thyroid FNACs were retrieved, out of which 209 cases of STN were chosen for this study. The Bethesda system for reporting thyroid cytopathology (TBSRTC) was used for analysis. Their FNACs diagnoses were compared with histopathological diagnoses. Results: Among 209 FNACs, 88 (42.1%) had non-neoplastic lesions, 6 (2.9%) had atypia of undetermined significance/follicular lesions of undetermined significance (AUS/FLUS), 52 (24.9%) had follicular neoplasm/suspicious for a follicular neoplasm (FN/SFN), 33 (15.8%) were suspicious for malignancy and 18 (8.6%) had malignant cytology. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of FNAC in STN cases were 94.4%, 97.6%, 95.8%, 98.1% and 93.2% respectively. Conclusion: Our study concluded that FNAC reporting using TBSRTC highly correlated with the histopathological diagnosis and our results were comparable with published data. The FNAC diagnosis helps in triaging patients with STN and identifies those who require surgical intervention. It is a simple, convenient, cost effective, sensitive, specific, safe and accurate initial diagnostic method for the preoperative evaluation of STN.
机译：背景：细针穿刺细胞学检查（FNAC）是评估孤立性甲状腺结节（STN）的有用诊断方法。在大多数情况下，它可以区分良性和恶性病变。目的：本研究旨在确定FNAC在STN评估中的实用性和诊断准确性。材料和方法：在这项回顾性研究中，总共检索了483例甲状腺FNAC，其中选择了209例STN。使用用于报告甲状腺细胞病理学的Bethesda系统（TBSRTC）进行分析。将他们的FNAC诊断与组织病理诊断进行比较。结果：在209例FNAC中，有88例（42.1％）有非肿瘤性病变，有6例（2.9％）有非典型性非典型性病变/有未确定性的滤泡性病变（AUS / FLUS），有52例（24.9％）具滤泡性肿瘤/可疑滤泡性肿瘤（FN / SFN）中，有33例（15.8％）可疑为恶性，18例（8.6％）为恶性细胞学。 FNAC在STN病例中的敏感性，特异性，准确性，阳性预测值和阴性预测值分别为94.4％，97.6％，95.8％，98.1％和93.2％。结论：我们的研究得出结论，使用TBSRTC的FNAC报告与组织病理学诊断高度相关，我们的结果与已发表的数据相当。 FNAC诊断有助于对STN患者进行分类，并确定需要手术干预的患者。这是一种用于STN术前评估的简单，方便，具有成本效益，灵敏，特异，安全和准确的初始诊断方法。

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