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首页> 外文期刊>Journal of Cardiovascular Development and Disease >Takotsubo Cardiomyopathy: A Long Term Follow-up Shows Benefit with Risk Factor Reduction
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Takotsubo Cardiomyopathy: A Long Term Follow-up Shows Benefit with Risk Factor Reduction

机译：Takotsubo心肌病：长期随访显示降低风险因素可带来益处

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Only sparse data was available on long-term of Takotusbo Cardiomyopathy (TC). Previous studies suggested prognosis is not necessarily benign. We report the long-term follow-up of 12 TC patients actively managed with risk factor reduction. Retrospective analysis of all patients diagnosed with TC at our hospital between 1998 and 2010. We identified 12 patients with TC among 1651 cases of emergent left heart catheterization over 12 years. Mean follow-up time was 8.3 ± 3.6 years. All were female, 87% had hypertension, 25% had history of Coronary Artery Disease (CAD), 67% had hyperlipidemia, 44% had some preceding emotional trauma, and 44% had some physical/physiological stress. Previous studies have shown that over 50% of TC patients experience future cardiac events, and 10% have a recurrence of TC. Patients were prescribed therapeutic lifestyle changes (TLC) and guideline directed medical therapy (GDMT) for aggressive risk factor reduction. TLC included diet, exercise, and cardiac rehabilitation. GDMT often included aspirin, beta-blockers, ACE-inhibitors, and statins. Follow-up echocardiograms showed recovery and maintenance of the ejection fraction. There was no cardiac mortality and no recurrences of TC. Aggressive risk factor reduction with TLC and GDMT may be effective in improving the long term outcomes of patients with TC.
机译：长期使用Takotusbo心肌病（TC）的数据稀少。先前的研究表明预后不一定是良性的。我们报告了通过降低危险因素积极治疗的12例TC患者的长期随访。回顾性分析1998年至2010年间在我院诊断为TC的所有患者。我们在12年内的1651例紧急左心导管中发现12例TC。平均随访时间为8.3±3。6年。全部为女性，有87％有高血压，有25％有冠心病病史，有67％有高脂血症，有44％有过先前的情感创伤，有44％有一定的生理/生理压力。先前的研究表明，超过50％的TC患者会发生未来的心脏事件，而10％的TC会复发。为患者开具治疗生活方式改变（TLC）和指导性药物治疗（GDMT）的处方，以降低积极的危险因素。 TLC包括饮食，运动和心脏康复。 GDMT通常包括阿司匹林，β受体阻滞剂，ACE抑制剂和他汀类药物。后续超声心动图显示射血分数恢复和维持。没有心脏死亡率，也没有TC复发。用TLC和GDMT积极降低危险因素可能有效改善TC患者的长期结局。

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