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首页> 外文期刊>Journal of Clinical Medicine Research >Endometrial Assessment: When Is It Necessary?
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Endometrial Assessment: When Is It Necessary?

机译：子宫内膜评估：什么时候需要？

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Background: Endometrial cancer is the fourth most common cancer among women and the most common malignant neoplasm of the female genital tract in the USA. The onset is usually after the age of 50 and prognosis depends on the stage of disease at diagnosis. We aimed at determining the prevalence of high-risk endometrial lesions in women of different ages to establish a protocol for the indication of invasive diagnostic procedures. Methods: A retrospective study was conducted based on the descriptive and statistical analysis of histopathological records of 2,931 patients who underwent uterine curettage between January 2001 and December 2011 at our institution. Results: The risk of endometrial malignancy was about 10 times higher in patients aged 50 years or older than that in younger women. However, women with abnormal uterine bleeding had a higher prevalence of high-risk conditions, regardless of age. Conclusion: Atypical and complex endometrial hyperplasia and carcinoma can affect women of all ages, but are more common in patients 50 years of age or older. Thus, endometrial sampling is recommended as a routine procedure for all women 50 years of age or older with clinical indications of the disease and as a screening procedure for those undergoing hysterectomy.J Clin Med Res. 2014;6(1):21-25 doi: http://dx.doi.org/10.4021/jocmr1684w
机译：背景：子宫内膜癌是女性中第四大最常见的癌症，也是美国女性生殖道最常见的恶性肿瘤。发病通常在50岁以后，预后取决于诊断时的疾病阶段。我们旨在确定不同年龄妇女的高危子宫内膜病变的患病率，以建立一种指示性侵入性诊断程序的协议。方法：对2001年1月至2011年12月在我院行刮宫手术的2931例患者的组织病理学记录进行描述和统计分析，进行回顾性研究。结果：年龄在50岁或以上的患者子宫内膜恶性肿瘤的风险比年轻女性高约10倍。但是，子宫出血异常的妇女无论年龄大小，其高危状况的患病率均较高。结论：非典型和复杂的子宫内膜增生和癌可以影响所有年龄段的女性，但在50岁以上的患者中更常见。因此，对于所有50岁以上且具有该疾病临床指征的女性，建议将子宫内膜取样作为常规程序，并建议将其用于子宫切除术的筛查程序.J Clin Med Res。 2014; 6（1）：21-25 doi：http://dx.doi.org/10.4021/jocmr1684w

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