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首页> 外文期刊>Journal of Clinical Medicine Research >Incidence of Vitamin D Insufficiency in Coastal South-Eastern US Patient Population With Cardiovascular Disease
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Incidence of Vitamin D Insufficiency in Coastal South-Eastern US Patient Population With Cardiovascular Disease

机译：美国东南沿海心血管病患者维生素D功能不足的发生率

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Background: Vitamin D insufficiency is increasingly gaining prominence as an associated cardiovascular disease (CVD) risk factor, often thought to be an issue in colder climates and higher altitudes. The intent of this study was to ascertain vitamin D levels in the southern Alabama gulf-coast region that has a high number of sunny days along with an annual average elevated UV ray index. Methods: An observational retrospective study of 204 patients with established CVD treated at the University of South Alabama’s Heart Center from January 2007 through January 2013 was undertaken. One-way ANOVA analyses were performed to determine any significant difference in the mean 25-hydroxyvitamin D (25(OH)D) serum based on gender and also based on race/ethnicity. Further, odds ratio (OR) was computed to ascertain if there was a relationship between vitamin D insufficiency and elevated body mass index (BMI). Results: Out of 204 patients, 53.4% (n = 109) were found to have vitamin D insufficiency (25(OH)D = 20.1 ng/mL), while 46.6% (n = 95) were within the normal range (25(OH)D = 37.8 ng/mL). The mean 25(OH)D of the entire group was 28.3, indicating a general trend of vitamin D insufficiency for patients treated at the cardiology clinics. Conclusion: This study established the prevalence of vitamin D insufficiency in the hot and high UV ray index climate of the coastal south-eastern United States. Also, it revealed the relationship of increased BMI with low 25(OH)D serum level. More extensive studies should be conducted in similar climates to further assess vitamin D insufficiency.J Clin Med Res. 2014;6(6):469-475doi: http://dx.doi.org/10.14740/jocmr1953w
机译：背景：维生素D缺乏症日益成为一种相关的心血管疾病（CVD）危险因素，通常被认为是寒冷气候和高海拔地区的一个问题。这项研究的目的是确定阿拉巴马州南部海湾沿岸地区的维生素D含量，该地区阳光充足，年平均紫外线指数更高。方法：从2007年1月至2013年1月，在南阿拉巴马大学心脏中心对204例已建立的CVD患者进行了观察性回顾性研究。进行了单向方差分析，以确定基于性别以及种族/民族的平均25-羟基维生素D（25（OH）D）血清中的任何显着差异。此外，计算比值比（OR）以确定维生素D功能不足与体重指数（BMI）升高之间是否存在关系。结果：在204例患者中，发现53.4％（n = 109）患有维生素D功能不足（25（OH）D = 20.1 ng / mL），而46.6％（n = 95）处于正常范围内（25（ OH）D = 37.8 ng / mL）。整个组的平均25（OH）D为28.3，表明在心脏病诊所接受治疗的患者维生素D缺乏的总体趋势。结论：这项研究确定了美国东南沿海热和高紫外线指数气候中维生素D不足的患病率。此外，它揭示了BMI升高与低25（OH）D血清水平的关系。应该在类似的气候下进行更广泛的研究，以进一步评估维生素D的不足。 2014; 6（6）：469-475doi：http://dx.doi.org/10.14740/jocmr1953w

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