• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Dementia & Neuropsychologia >Lewy and his inclusion bodies: Discovery and rejection
【24h】

Lewy and his inclusion bodies: Discovery and rejection

机译：路易及其包容性身体：发现与拒绝

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Fritz Jacob Heinrich Lewy described the pathology of Paralysis agitans [Parkinson disease] and was the first to identify eosinophilic inclusion bodies in neurons of certain brain nuclei, later known as Lewy bodies, the pathological signature of the Lewy body diseases. In 1912, he published his seminal study, followed soon after by an update paper, and 10 years later, in 1923, by his voluminous book, where he exhaustively described the subject. The publication provided extensive information on the pathology of Paralysis agitans, and the entirely novel finding of eosinophilic inclusion bodies, which would become widely recognized and debated in the future. His discovery was acknowledged by important researchers who even named the structure after him. However, after his last publication on the issue, inexplicably, he never mentioned his histopathological discovery again. Despite several hypotheses, the reasons that led him to neglect (reject) the structure which he so preeminently described have remained elusive.
机译：弗里茨·雅各布·海因里希·路易（Fritz Jacob Heinrich Lewy）描述了焦虑性瘫痪（帕金森病）的病理学，并且是第一个在某些脑核神经元中识别嗜酸性包涵体的组织，后来称为路易体，是路易体病的病理特征。在1912年，他发表了他的开创性研究，随后发表了一篇最新论文，并在10年后的1923年发表了他的大量著作，在其中详尽地描述了这个主题。该出版物提供了有关震颤麻痹的病理学以及嗜酸性包涵体的全新发现的广泛信息，这些发现将在未来得到广泛认可和争论。重要的研究人员认可了他的发现，甚至以他的名字命名了该结构。但是，在最后一次发表有关该问题的文章后，他莫名其妙地再也没有提及他的组织病理学发现。尽管有几种假设，导致他忽略（拒绝）他如此描述的结构的原因仍然难以捉摸。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号