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首页> 外文期刊>Dementia and Geriatric Cognitive Disorders Extra >Validation of the Malay Version of Addenbrooke’s Cognitive Examination III in Detecting Mild Cognitive Impairment and Dementia
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Validation of the Malay Version of Addenbrooke’s Cognitive Examination III in Detecting Mild Cognitive Impairment and Dementia

机译：在检测轻度认知障碍和痴呆症中对阿登布鲁克认知考试III的马来语版本的验证

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Background/Aims: This study aimed to investigate the validity and reliability of the Malay version of Addenbrooke’s Cognitive Examination III (ACE-III) for detecting mild cognitive impairment (MCI) and dementia. Methods: A total of 152 participants (dementia = 53, MCI = 38, controls = 61) were recruited from two teaching hospitals. The Malay version of ACE-III was translated following the standard guidelines for cross-cultural adaptation of measure. All the participants were assessed with the Malay version of ACE-III and Mini-Mental State Examination (MMSE). Results: The reliability of the Malay version of ACE-III was good with Cronbach’s α coefficient of 0.829 and intraclass correlation coefficient of 0.959. There was a strong positive correlation between the Malay version of ACE-III and MMSE (r = 0.806). Age (r = –0.335) and years of education (r = 0.536) exerted a significant correlation with total score performance. The cutoff score to discriminate dementia from healthy controls was 74/75 (sensitivity = 90.6%, specificity = 82.0%) whereas to discriminate MCI, the cutoff score was 77/78 (sensitivity = 63.2%, specificity = 63.9%). The diagnostic accuracy of ACE-III was higher than that of MMSE in the detection of dementia (area under the curve: ACE-III = 0.929 vs. MMSE = 0.915). Conclusions: The Malay version of ACE-III demonstrated to be a reliable and valid screening tool for dementia.
机译：背景/目的：本研究旨在调查马来版阿登布鲁克认知测试III（ACE-III）在检测轻度认知障碍（MCI）和痴呆症方面的有效性和可靠性。方法：从两家教学医院招募了152名参与者（痴呆症= 53，MCI = 38，对照= 61）。 ACE-III的马来语版本是根据跨文化适应措施的标准指南进行翻译的。所有参与者都接受了马来版的ACE-III和小精神状态考试（MMSE）评估。结果：马来版ACE-III的可靠性良好，Cronbachα系数为0.829，组内相关系数为0.959。 ACE-III的马来版本与MMSE之间有很强的正相关性（r = 0.806）。年龄（r = –0.335）和受教育年限（r = 0.536）与总成绩表现显着相关。区分痴呆症与健康对照组的临界值是74/75（敏感性= 90.6％，特异性= 82.0％），而区分MCI的临界值是77/78（敏感性= 63.2％，特异性= 63.9％）。在痴呆症的检测中，ACE-III的诊断准确性高于MMSE（曲线下面积：ACE-III = 0.929 vs. MMSE = 0.915）。结论：马来版的ACE-III被证明是一种可靠且有效的痴呆筛查工具。

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