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首页> 外文期刊>Journal of Hainan Medical University >Clinical significance of serum tumor markers CA153, CA125, CA72-4 and FIB, IL-6 levels detection in ovarian cancer
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Clinical significance of serum tumor markers CA153, CA125, CA72-4 and FIB, IL-6 levels detection in ovarian cancer

机译：血清肿瘤标志物CA153，CA125，CA72-4和FIB，IL-6水平检测在卵巢癌中的临床意义

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Objective: To investigate the clinical significance of serum tumor markers CA153, CA125, CA72-4 and FIB, IL-6 levels in the detection of ovarian cancer. Methods: A total of 40 patients with ovarian carcinoma treated in our hospital from September 2015 to June 2017 were selected as the ovarian cancer group; 40 patients with benign ovarian tumors in the same period were selected as the benign ovarian tumor group; 40 healthy subjects were selected as the control group. The levels of tumor markers CA153, CA125, CA72-4 and FIB, IL-6 were compared between the three groups. Results: The CA153, CA125, CA72-4 and FIB, IL-6 levels of the ovarian cancer group were significantly higher than those in benign ovarian tumor group and the control group; these levels in the benign ovarian tumor group was not significantly different from those in the control group. With the increase of clinical phase, the levels of CA153, CA125 and CA72-4 in patients with ovarian cancer were gradually increased, and the levels in phase III and IV were significantly higher than those in phase II and in phase I; and the CA125 in phase II was significantly higher than that in phase I. The levels of FIB and IL-6 in phase II and in phase III, IV were significantly higher than those in phase I; the IL-6 level in phase III, IV was significantly higher than that in phase II. Conclusion: Serum tumor markers CA153, CA125, CA72-4 and FIB, IL-6 levels for ovarian cancer detection can be helpful for clinical diagnosis and worthy of promotion.
机译：目的：探讨血清肿瘤标志物CA153，CA125，CA72-4和FIB，IL-6水平在卵巢癌检测中的临床意义。方法：选择2015年9月至2017年6月我院收治的40例卵巢癌患者作为卵巢癌组。选择同期卵巢良性肿瘤40例作为卵巢良性肿瘤组。选择40名健康受试者作为对照组。在三组之间比较了肿瘤标志物CA153，CA125，CA72-4和FIB，IL-6的水平。结果：卵巢癌组的CA153，CA125，CA72-4和FIB，IL-6水平明显高于卵巢良性肿瘤组和对照组。卵巢良性肿瘤组的这些水平与对照组无显着差异。随着临床分期的增加，卵巢癌患者CA153，CA125和CA72-4水平逐渐升高，III，IV期明显高于II期和I期。 II期和III，IV期的FIB和IL-6水平明显高于I期; CA125在II期明显高于I期。 III，IV期的IL-6水平明显高于II期。结论：检测卵巢癌的血清肿瘤标志物CA153，CA125，CA72-4和FIB，IL-6水平有助于临床诊断，值得推广。

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