...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Hainan Medical University >Determination of serum inflammatory factors in different pathogenic bloodstream infections and judgment value on the degree of disease severity and prognosis
【24h】

Determination of serum inflammatory factors in different pathogenic bloodstream infections and judgment value on the degree of disease severity and prognosis

机译：不同病原性血液感染中血清炎性因子的测定及其对疾病严重程度和预后的判断价值

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objective: To investigate the serum inflammatory cytokines expression in different pathogens and to explore the value of serum inflammatory cytokines in judging the severity of disease and assessing prognosis. Methods: We retrospectively analyzed 90 cases of bloodstream infections admitted to our hospital from October 2016 to November 2017 and regarded it as observation group, while the control group was 80 patients with negative blood cultures over the same period. Serum inflammatory factors PCT, C-reactive protein (CRP), white blood cell count (WBC), neutrophil percentage (NEUT) and Endotoxin levels were compared between the two groups.The levels of serum inflammatory factors PCT, CRP, WBC, NEUT and Endotoxin in patients with Gram-positive(G+), Gram-negative (G-), treatment improvement and treatment ineffective group were compared. Result: The levels of PCT, CRP, WBC, NEUT and Endotoxin in patients with positive blood flow culture were significantly higher than those with negative blood culture. Compared with the G+ group, the levels of PCT, CRP, WBC and Endotoxin in the G- group were significantly higher. There was no significant difference in the level of NEUT in two groups. Compared with the treatment-ineffective group, the therapeutic improvement group PCT, CRP, WBC, NEUT and Endotoxin levels decreased significantly. The levels of PCT, CRP, WBC,NEUT and endotoxin in patients with moderate and severe bloodstream infections were significantly higher than those with mild infections; the levels of PCT, CRP, WBC, NEUT and endotoxin in patients with moderate infection were significantly higher than those with mild infections, and all has statistical significance. Conclusion: PCT, CRP, WBC, NEUT and Endotoxin can be used as auxiliary diagnostic indicators of bloodstream infections, which can be used to judge the severity of bloodstream infection and evaluate the prognosis.
机译：目的：探讨血清中炎性细胞因子在不同病原体中的表达，探讨血清炎性细胞因子在判断病情和评估预后中的价值。方法：回顾性分析我院2016年10月至2017年11月收治的90例血流感染病例，将其作为观察组，对照组为同期血培养阴性的80例患者。比较两组患者的血清炎性因子PCT，C反应蛋白（CRP），白细胞计数（WBC），中性粒细胞百分率（NEUT）和内毒素水平。比较革兰氏阳性（G +），革兰氏阴性（G-），治疗改善和治疗无效的患者的内毒素。结果：血培养阳性的患者的PCT，CRP，WBC，NEUT和内毒素水平显着高于血培养阴性的患者。与G +组相比，G-组的PCT，CRP，WBC和内毒素水平显着更高。两组的NEUT水平无明显差异。与治疗无效组相比，治疗改善组的PCT，CRP，WBC，NEUT和内毒素水平显着降低。中度和重度血液感染患者的PCT，CRP，WBC，NEUT和内毒素水平显着高于轻度感染患者。中度感染患者的PCT，CRP，WBC，NEUT和内毒素水平显着高于轻度感染患者，均具有统计学意义。结论：PCT，CRP，WBC，NEUT和内毒素可作为血流感染的辅助诊断指标，可用于判断血流感染的严重程度和评估预后。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号