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首页> 外文期刊>Journal of International Medical Research >Comparison of Anastomotic Leakage and Stricture Formation following Layered and Stapler Oesophagogastric Anastomosis for Cancer: A Prospective Randomized Controlled Trial
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Comparison of Anastomotic Leakage and Stricture Formation following Layered and Stapler Oesophagogastric Anastomosis for Cancer: A Prospective Randomized Controlled Trial

机译：分层和吻合器食管胃吻合术治疗癌症后吻合口漏和狭窄形成的比较：一项前瞻性随机对照试验

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摘要

The objective of this prospective, randomized, controlled trial, conducted from May 2002 to December 2007, was to compare post-operative anastomotic leakage and stricture formation following layered manual versus stapler oesophagogastric anastomosis in patients who underwent resection of oesophageal or gastric cardia carcinoma. Patients (n = 516) were randomized to receive either layered manual or circular stapled oesophagogastric anastomosis. Mean follow-up time was > 12 months. Anastomotic leakage occurred in one (0.4%) patient in the layered group and six (2.2%) in the stapler group; no statistically significant between-group difference. After operation, two (0.8%) patients in the layered group and 13 (5.0%) in the stapler group developed a benign oesophageal stricture; the difference between the groups was statistically significant. Compared with stapler anastomosis, layered manual anastomosis may significantly reduce the incidence of anastomotic strictures. This method is easy to apply and could be used as an alternative procedure for oesophagogastric anastomosis after resection for oesophageal or cardia carcinoma.
机译：这项于2002年5月至2007年12月进行的前瞻性，随机，对照试验的目的是比较分层切除的手动食管吻合器与吻合器食管胃吻合术在切除食管或胃card门癌患者中的术后吻合口漏和狭窄形成情况。患者（n = 516）被随机分配接受分层人工或圆形吻合食管胃吻合术。平均随访时间> 12个月。分层组中一名（0.4％）患者发生吻合口漏，订书机组中六名（2.2％）患者发生吻合口漏;组间无统计学差异。手术后，分层组中有2例（0.8％）患者和吻合器组中有13例（5.0％）患者出现了良性食管狭窄。两组之间的差异具有统计学意义。与吻合器吻合术相比，分层人工吻合术可显着降低吻合口狭窄的发生率。该方法易于应用，可作为食管胃癌或card门癌切除术后食管胃吻合的替代方法。

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