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首页> 外文期刊>Journal of International Medical Research >Comparison of neutrophil–lymphocyte ratio and platelet–lymphocyte ratio in patients with thyroiditis and papillary tumors
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Comparison of neutrophil–lymphocyte ratio and platelet–lymphocyte ratio in patients with thyroiditis and papillary tumors

机译：甲状腺炎和乳头状瘤患者中性粒细胞-淋巴细胞比和血小板-淋巴细胞比的比较

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Objective The neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) have recently been introduced as prognostic markers of thyroid cancer and strong inflammatory markers. The study was performed to investigate the association of the PLR and NLR with thyroid inflammation and papillary cancer. Methods Patients with thyroiditis and patients with papillary carcinomas were compared with sex-, age-, and body mass index-matched healthy controls. The NLR and PLR were calculated and compared among the three groups. Results The NLR was significantly higher in patients with thyroiditis and non-significantly higher in patients with papillary cancer than in healthy controls. The PLR was significantly higher in both patients with thyroiditis and papillary cancer than in healthy controls. Like the NLR, the PLR was not different between patients with thyroiditis and papillary cancer. The NLR was significantly and positively associated with the PLR and white blood cell count. Conclusion The PLR and NLR showed similar results in both thyroid inflammation and cancer. It seems difficult to obtain clear results in separating cancer from inflammatory events using these parameters. We suggest using them as supportive parameters of thyroid papillary cancer or inflammation.
机译：目的最近已引入嗜中性粒细胞-淋巴细胞比（NLR）和血小板-淋巴细胞比（PLR）作为甲状腺癌的预后指标和强烈的炎症指标。进行该研究以调查PLR和NLR与甲状腺炎症和乳头状癌的关系。方法将甲状腺炎患者和乳头状癌患者与性别，年龄和体重指数匹配的健康对照组进行比较。计算了三组的NLR和PLR并进行了比较。结果甲状腺炎患者的NLR显着高于健康对照组，而乳头状癌患者的NLR则无明显升高。甲状腺炎和乳头状癌患者的PLR均显着高于健康对照组。像NLR一样，甲状腺炎和乳头状癌患者的PLR也没有差异。 NLR与PLR和白细胞计数显着正相关。结论PLR和NLR在甲状腺炎症和癌症中显示出相似的结果。使用这些参数似乎很难在将癌症与炎症事件分离中获得明确的结果。我们建议将它们用作甲状腺乳头状癌或炎症的支持参数。

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