首页> 外文期刊>Journal of King Saud University >Phytochemical screening and antimicrobial potentials of Borreria sps (Rubiaceae)
【24h】

Phytochemical screening and antimicrobial potentials of Borreria sps (Rubiaceae)

机译: Borreria sps(茜草科)的植物化学筛选和抗菌潜能

获取原文
           

摘要

Successive hexane, acetone, ethanol and methanolic whole plant extracts of the Borreria sps were investigated for phytochemical screening and assessed for antimicrobial activity. Phytochemical analysis of Borreria sps extracts revealed the presence of phenolics, flavonoids and tannins. Among them, Borreria laevicaulis hexane extracts were found to be most effective showing the largest zone of inhibition against Staphylococcus aureus (22.15 mm) and Candida albicans (25.65 mm). Further studies indicated that the minimum inhibitory concentration of B. laevicaulis hexane extracts was found to be 62.5 μg/ml against S. aureus and 250 μg/ml against C. albicans and the zone of inhibitions was significantly higher than nystatin (positive control). Together, we provide new insights of the B. laevicaulis as a potential candidate for antimicrobial drug discovery using in vitro studies that might be useful to treat human infectious diseases and antibiotic resistant pathogens.
机译:研究了连续的正己烷,丙酮,乙醇和甲醇的Borreria sps全植物提取物进行植物化学筛选,并评估了其抗菌活性。孢霉属提取物的植物化学分析表明存在酚类,类黄酮和单宁酸。其中,发现鲍氏疏螺旋体的己烷提取物最有效,对金黄色葡萄球菌(22.15 mm)和白色念珠菌(25.65 mm)的抑制作用最大。进一步的研究表明,发现酿酒酵母己烷提取物对金黄色葡萄球菌的最低抑菌浓度为62.5μg/ ml,对白色念珠菌的抑菌浓度为250μg/ ml,抑菌圈明显高于制霉菌素(阳性对照)。在一起,我们使用体外研究提供了对B. laevicaulis作为抗微生物药物发现的潜在候选者的新见解,这些研究可能对治疗人类传染病和抗生素耐药性病原体有用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号