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首页> 外文期刊>Journal of International Medical Research >Short- and Long-Term Effect of Nifedipine on the Visual Field in Patients with Presumed Vasospasm
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Short- and Long-Term Effect of Nifedipine on the Visual Field in Patients with Presumed Vasospasm

机译:硝苯地平对假定的血管痉挛患者视野的短期和长期影响

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It is assumed that the ocular circulation may be involved in the vasospastic syndrome and patients with vasospasm have visual field defects that are neither ophthalmologically nor neurologically explainable. A retrospective study showed that 20 mg sustained-release nifedipine treatment given orally may be helpful in these cases. There was a marked short-term effect in cases with proven peripheral vasospasms but not in similar cases without such vasospasms. The study also showed that the effect could last for up to 12 months when 20 mg nifedipine was given twice daily but the long-term effect was slightly less than the short-term effect. A number of patients had to discontinue nifedipine treatment due to side-effects.
机译:假定眼循环可能与血管痉挛综合征有关,血管痉挛患者的视野缺损在眼科和神经学上均无法解释。一项回顾性研究表明,口服给予的硝苯地平缓释剂20 mg在这些情况下可能会有帮助。在已证实的周围血管痉挛的病例中有明显的短期作用,但在没有这种血管痉挛的类似病例中没有明显的短期作用。该研究还表明,每天两次服用20mg硝苯地平时,该作用可持续长达12个月,但长期作用比短期作用稍小。由于副作用,许多患者不得不停止硝苯地平治疗。

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