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首页> 外文期刊>Journal of medical bacteriology. >The Determination of the Antimicrobial Susceptibility and Antimicrobial Resistance Gene Patterns in L. monocytogenes
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The Determination of the Antimicrobial Susceptibility and Antimicrobial Resistance Gene Patterns in L. monocytogenes

机译：单核细胞增生李斯特菌抗菌药敏性和耐药性基因模式的确定

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Background: Listeriosis, a fatal disease for vulnerable groups, has become common in the last decade due to extensive consumption of dairy and meat products. Listeria monocytogenes is an important foodborne opportunistic human pathogen and causal agent of listeriosis. There is a little information about the antibiotic susceptibility and resistance genes pattern of L. monocytogenes. Methods: The present study aimed to evaluate the antibiotic susceptibility and resistance genes pattern of L. monocytogenes isolates from different clinical and environmental sources. Results: The results showed that 88% of the isolates are resistant to streptomycin and 83% to TMP-SMX. Polymerase chain reaction (PCR) amplification of resistance genes showed that the prevalence of ermA, ermB, strA, tetS, tetA, and ermC genes in L. monocytogenes isolates were 0% (0/55), 10.9% (6/55), 78.81% (43/55), 0% (0/55), 27.27% (15/55), and 0% (0/55), respectively. Conclusion: The resistance of the isolates to the antibiotics represents a potential public health risk and indicates the necessity of the bacteriological controls to reduce the contamination of the food samples.
机译：背景：李斯特氏菌病是弱势群体的致命疾病，由于乳制品和肉类产品的大量消费，在过去十年中已经很普遍。单核细胞增生李斯特菌是重要的食源性机会性人类病原体和李斯特菌病的病因。关于单核细胞增生李斯特氏菌的抗生素敏感性和耐药基因模式的信息很少。方法：本研究旨在评估来自不同临床和环境来源的单核细胞增生李斯特菌菌株的抗生素敏感性和耐药基因模式。结果：结果显示88％的分离株对链霉素具有抗性，而83％的TMP-SMX具有抗性。耐药基因的聚合酶链反应（PCR）扩增显示单核细胞增生李斯特菌中ermA，ermB，strA，tetS，tetA和ermC基因的患病率为0％（0/55），10.9％（6/55），分别为78.81％（43/55），0％（0/55），27.27％（15/55）和0％（0/55）。结论：分离物对抗生素的耐药性代表潜在的公共卫生风险，并表明需要采取细菌学控制措施以减少食品样品的污染。

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